Graded
The US health department published a draft policy under which it would not act against pharmacies that make BPC-157 on a prescription for a named patient, until the FDA decides by rule. It is still not an approved medicine.
PL

NMN

nicotinamide mononucleotide · β-NMN

A substance the body turns into NAD+. Sold as a dietary supplement.

This site is for information and education only. It does not promote or encourage the use or purchase of the substances described and is not medical advice. Many are not authorised as medicines and their safety has not been established. We sell nothing and have no ties to sellers. For health decisions, consult a doctor.

Type
NAD+ and related
Stage
Still being studied
Safety
Little data
Doping
Not on the list, WADA 2026
Risk of fakes
Not known
Checked
Not yet

Safety. Studies last weeks, not years. A consulting firm reports that the EU food safety agency EFSA gave one NMN product a positive safety opinion on 11 May 2026, for adults, excluding pregnancy and breastfeeding. We have not read the opinion itself. Sources: study 1, CIRS.

Risk of fakes. We found no tests of products sold outside pharmacies.

Is it legal

How much research exists

Scientific papers
1555
Studies with random groups
17
Registered studies in people
33

Scientific papers per year 2015–2025

These are search results. A count shows how much exists, not how good the studies are. 1 Nov 2026.

What studies show

  • CLonger life

    Not clear. Studies are short and measure NAD in blood or fitness tests, not ageing. One found better muscle response to insulin and another found no change.

Reported side effects

What doctors, patients and companies reported to the US medicines agency (FDA), and single cases described in medical journals. A report says what happened to someone after taking the substance. It does not prove the substance caused it, and it does not say how often it happens. Reports do not change any grade.

FDA reports come from openFDA, cases from a PubMed search. The editors have not read these cases yet. Titles stay in the original language. As of 3 Nov 2026.

Studies we have read

StudiesKind of studyWho was studiedPeopleDurationDose as studiedWho paid
Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study.GeroScience 2024Random groupsOlder adults6012 wk250 mg dailyUnknown
The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.GeroScience 2023Random groupsHealthy middle-aged adults809 wk300, 600 or 900 mg dailyUnknown
Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study.The Journal of clinical endocrinology and metabolism 2023Random groupsOverweight or obese adults aged 45 or more304 wk1000 mg twice dailyManufacturer
Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial.Scientific reports 2023Random groupsHealthy middle-aged adults3612 wk125 mg twice dailyUnknown
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.Science (New York, N.Y.) 2021Random groupsPostmenopausal women with prediabetes, overweight or obese–10 wk–Unknown

More papers we found

We found these papers automatically in PubMed. The editors have not read them yet, and they do not affect any grade. Titles stay in the original language.

All papers and studies we found (300)

Short answers

Does NMN work?
A substance the body turns into NAD+. Sold as a dietary supplement. Longer life: grade C, not clear. Studies are short and measure NAD in blood or fitness tests, not ageing. One found better muscle response to insulin and another found no change.
Is NMN legal?
PL: No approval. The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. This covers medicines, not supplements. EU: No approval. The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). This covers medicines, not supplements. US: No approval. The FDA drug register has no such medicine.
Is NMN banned in sport?
Not on the list, WADA 2026.
Is NMN safe?
Little data. Studies last weeks, not years. A consulting firm reports that the EU food safety agency EFSA gave one NMN product a positive safety opinion on 11 May 2026, for adults, excluding pregnancy and breastfeeding. We have not read the opinion itself.

Compare with NAD+Plain text for machines