Graded
The US health department published a draft policy under which it would not act against pharmacies that make BPC-157 on a prescription for a named patient, until the FDA decides by rule. It is still not an approved medicine.
PL

Longer life

No substance on this site has been shown to extend human life. Studies in people measure short-term signs, such as blood results.

First, legal options with stronger studies

  • Regular physical activity, including strength and endurance work.
  • Not smoking.
  • Treating high blood pressure, high cholesterol and diabetes with a doctor.
  • Check-ups recommended for your age, sleep, and time with other people.

What studies found for specific substances

Sorted alphabetically. Order does not imply a recommendation.

  • DEpitalon

    Fruit flies lived 11% to 16% longer. There are no studies with random groups in people.

  • DMOTS-c

    Mouse studies only. Papers tagged as studies with random groups measure MOTS-c in blood and do not give it to people.

  • ENAD+

    A 2026 review found no study of the effects of NAD+ itself given by drip or injection. Studies test NMN and NR, which the body turns into NAD+, and their results on health are mixed or show no effect.

  • CNMN

    Studies are short and measure NAD in blood or fitness tests, not ageing. One found better muscle response to insulin and another found no change.

  • CRapamycin

    Mice clearly lived longer. Studies in people are short, measure indirect signs and show no steady benefit.