Graded
Ministerstwo zdrowia USA opublikowało projekt zasad, według którego nie będzie ścigać aptek przygotowujących BPC-157 na receptę dla konkretnej osoby, dopóki FDA nie zdecyduje w przepisach. To nadal nie jest dopuszczony lek.
EN

Tesamorelina

Wróć do opisu substancji

Prace naukowe

BadaniaRodzaj badaniaRok
Efficacy and Safety of Tesamorelin in People Living With HIV (PLWH) With Lipodystrophy: A Systematic Review and Meta-Analysis.J Int Assoc Provid AIDS CareAnaliza zbiorcza2026
Body composition, hepatic fat, metabolic, and safety outcomes of Tesamorelin, a GHRH analogue, in HIV-associated lipodystrophy: A meta-analysis of randomized controlled trials.Obes Res Clin PractAnaliza zbiorcza2026
Effects of Tesamorelin on Neurocognitive Impairment in Persons With HIV and Abdominal Obesity.J Infect DisZ losowaniem grup2025
Efficacy and safety of tesamorelin in people with HIV on integrase inhibitors.AIDSZ losowaniem grup2024
Growth Hormone Releasing Hormone Reduces Circulating Markers of Immune Activation in Parallel with Effects on Hepatic Immune Pathways in Individuals with HIV-infection and Nonalcoholic Fatty Liver Disease.Clin Infect DisZ losowaniem grup2021
Clinical Predictors of Liver Fibrosis Presence and Progression in Human Immunodeficiency Virus-Associated Nonalcoholic Fatty Liver Disease.Clin Infect DisZ losowaniem grup2021
Effects of tesamorelin on hepatic transcriptomic signatures in HIV-associated NAFLD.JCI InsightZ losowaniem grup2020
Effects of tesamorelin on non-alcoholic fatty liver disease in HIV: a randomised, double-blind, multicentre trial.Lancet HIVZ losowaniem grup2019
The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV.J Frailty AgingZ losowaniem grup2019
Fibroblast growth factor 21 decreases after liver fat reduction via growth hormone augmentation.Growth Horm IGF ResZ losowaniem grup2017
Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial.PLoS OneZ losowaniem grup2017
Predictors of Treatment Response to Tesamorelin, a Growth Hormone-Releasing Factor Analog, in HIV-Infected Patients with Excess Abdominal Fat.PLoS OneZ losowaniem grup2015
Population pharmacokinetic analysis of tesamorelin in HIV-infected patients and healthy subjects.Clin PharmacokinetZ losowaniem grup2015
The effects of tesamorelin on phosphocreatine recovery in obese subjects with reduced GH.J Clin Endocrinol MetabZ losowaniem grup2014
Growth hormone-releasing hormone effects on brain γ-aminobutyric acid levels in mild cognitive impairment and healthy aging.JAMA NeurolZ losowaniem grup2013
Metabolic effects of a growth hormone-releasing factor in obese subjects with reduced growth hormone secretion: a randomized controlled trial.J Clin Endocrinol MetabZ losowaniem grup2012
Effects of growth hormone–releasing hormone on cognitive function in adults with mild cognitive impairment and healthy older adults: results of a controlled trial.Arch NeurolZ losowaniem grup2012
Reduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin.Clin Infect DisZ losowaniem grup2012
Effects of tesamorelin on inflammatory markers in HIV patients with excess abdominal fat: relationship with visceral adipose reduction.AIDSZ losowaniem grup2011
Long-term safety and effects of tesamorelin, a growth hormone-releasing factor analogue, in HIV patients with abdominal fat accumulation.AIDSZ losowaniem grup2008
Metabolic effects of a growth hormone-releasing factor in patients with HIV.N Engl J MedZ losowaniem grup2007
Population pharmacokinetic and pharmacodynamic analysis of tesamorelin in HIV-infected patients and healthy subjects.J Pharmacokinet PharmacodynBez losowania grup2015
Relationship of adiponectin to endogenous GH pulse secretion parameters in response to stimulation with a growth hormone releasing factor.Growth Horm IGF ResBez losowania grup2011
Differing Presentations of Excess Visceral Abdominal Fat in People Living With HIV: Two Clinical Cases Highlighting Distinct Therapeutic Pathways With Tesamorelin and Glucagon-Like Peptide-1 Receptor Agonists.Clin Infect DisOpisy przypadków2026
Approach to the Patient With Lipodystrophy.J Clin Endocrinol MetabOpisy przypadków2022
Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review.Sex Med RevPrzegląd badań2026
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.Front Endocrinol (Lausanne)Przegląd badań2026
Injectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Implications.JBJS RevPrzegląd badań2026
Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives.Int J Mol SciPrzegląd badań2026
Pharmacologic Treatments for the Preservation of Lean Body Mass During Weight Loss.J Clin MedPrzegląd badań2026
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.J Am Acad Orthop Surg Glob Res RevPrzegląd badań2026
Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians.Am J Sports MedPrzegląd badań2026
Metabolic dysfunction-associated steatotic liver disease in people with HIV.Curr Opin HIV AIDSPrzegląd badań2025
CROI 2024: Neuropsychiatric Complications in People With HIV.Top Antivir MedPrzegląd badań2024
Causes and outcomes of hepatic fibrosis in persons living with HIV.Curr Opin HIV AIDSPrzegląd badań2022
Non-Alcoholic Steatohepatitis (NASH) - A Review of a Crowded Clinical Landscape, Driven by a Complex Disease.Drug Des Devel TherPrzegląd badań2021
Cardiovascular risk and dyslipidemia among persons living with HIV: a review.BMC Infect DisPrzegląd badań2017
Growth hormone deficiency and human immunodeficiency virus.Best Pract Res Clin Endocrinol MetabPrzegląd badań2017
Therapeutic augmentation of the growth hormone axis to improve outcomes following peripheral nerve injury.Expert Opin Ther TargetsPrzegląd badań2016
Growth hormone in the aging male.Best Pract Res Clin Endocrinol MetabPrzegląd badań2013
Pathophysiology of GHRH-growth hormone-IGF1 axis in HIV/AIDS.Rev Endocr Metab DisordPrzegląd badań2013
How to diagnose a lipodystrophy syndrome.Ann Endocrinol (Paris)Przegląd badań2012
Tesamorelin: a growth hormone-releasing factor analogue for HIV-associated lipodystrophy.Ann PharmacotherPrzegląd badań2012
Spotlight on tesamorelin in HIV-associated lipodystrophy.BioDrugsPrzegląd badań2011
Growth hormone axis treatments for HIV-associated lipodystrophy: a systematic review of placebo-controlled trials.HIV MedPrzegląd badań2011
Tesamorelin: a review of its use in the management of HIV-associated lipodystrophy.DrugsPrzegląd badań2011
Pathogenesis and treatment of HIV lipohypertrophy.Curr Opin Infect DisPrzegląd badań2011
Growth hormone-releasing factor agonists for the treatment of HIV-associated lipodystrophy.Curr Opin Investig DrugsPrzegląd badań2010
Epidemiology, assessment, and management of excess abdominal fat in persons with HIV infection.AIDS RevPrzegląd badań2010
Tesamorelin, a human growth hormone releasing factor analogue.Expert Opin Investig DrugsPrzegląd badań2009
Drug evaluation: tesamorelin, a synthetic human growth hormone releasing factor.Curr Opin Investig DrugsPrzegląd badań2006
Combined antiretroviral therapy with low- or normal-protein, high-calorie diets appears to induce significant deleterious electrocardiographic changes in a rodent model.Braz J Med Biol ResNa zwierzętach2026
Advances in the detection of growth hormone releasing hormone synthetic analogs.Drug Test AnalW probówce2021
The effect of growth hormone-releasing hormone on cognition and brain connectivity in adults with cognition ranging from normal to mild cognitive impairment.eNeurologicalSciInna praca2026
Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV (TRIUMPH): a clinical trial protocol.BMJ OpenInna praca2026
Analysis of growth hormone releasing hormone and its analogs in urine using nano liquid chromatography coupled with quadrupole/orbitrap mass spectrometry.J Pharm Biomed AnalInna praca2026
Carpal Tunnel Syndrome Attributed to Medication Use: A Pharmacovigilance Study.CureusInna praca2025
Dietary regimens appear to possess significant effects on the development of combined antiretroviral therapy (cART)-associated metabolic syndrome.PLoS OneInna praca2024
Chromatographic-mass spectrometric analysis of peptidic analytes (2-10 kDa) in doping control urine samples.J Mass SpectromInna praca2024
Cationic exchange SPE combined with triple quadrupole UHPLC-MS/MS for detection of GHRHs in urine samples.Anal BiochemInna praca2023
Effect of tesamorelin in people with HIV with and without dorsocervical fat: Post hoc analysis of phase III double-blind placebo-controlled trial.J Clin Transl SciInna praca2023
Probing for peptidic drugs (2-10 kDa) in doping control blood samples.Anal Sci AdvInna praca2022
An antibody-free, ultrafiltration-based assay for the detection of growth hormone-releasing hormones in urine at low pg/mL concentrations using nanoLC-HRMS/MS.J Pharm Biomed AnalInna praca2022
Tesamorelin improves fat quality independent of changes in fat quantity.AIDSInna praca2021
Delineating tesamorelin response pathways in HIV-associated NAFLD using a targeted proteomic and transcriptomic approach.Sci RepInna praca2021
Comparison of magnetic bead surface functionalities for the immunopurification of growth hormone-releasing hormones prior to liquid chromatography-high resolution mass spectrometry.J Chromatogr AInna praca2020
Peptide Ligation at High Dilution via Reductive Diselenide-Selenoester Ligation.J Am Chem SocInna praca2020
Comparison of visceral fat measurement by dual-energy X-ray absorptiometry to computed tomography in HIV and non-HIV.Nutr DiabetesInna praca2019
Visceral fat reduction with tesamorelin is associated with improved liver enzymes in HIV.AIDSInna praca2017
Qualitative identification of growth hormone-releasing hormones in human plasma by means of immunoaffinity purification and LC-HRMS/MS.Anal Bioanal ChemInna praca2016
Expanded test method for peptides >2 kDa employing immunoaffinity purification and LC-HRMS/MS.Drug Test AnalInna praca2015
Impact of Tesamorelin, a Growth Hormone-Releasing Factor (GRF) Analogue, on the Pharmacokinetics of Simvastatin and Ritonavir in Healthy Volunteers.Clin Pharmacol Drug DevInna praca2013
Neuroendocrinology: Tesamorelin can improve cognitive function.Nat Rev EndocrinolInna praca2012
Pathogenesis and treatment of human immunodeficiency virus lipodystrophy.Indian J Endocrinol MetabInna praca2012
Tesamorelin: a novel therapeutic option for HIV/HAART-associated increased visceral adipose tissue.Drugs Today (Barc)Inna praca2011
Tesamorelin: A hope for ART-induced lipodystrophy.J Pharm Bioallied SciInna praca2011
Tesamorelin for the treatment of excess abdominal fat in HIV-1-infected patients with lipodystrophy.Expert Rev Endocrinol MetabInna praca2011
Growth hormone and tesamorelin in the management of HIV-associated lipodystrophy.HIV AIDS (Auckl)Inna praca2011
Effects of a growth hormone-releasing hormone analog on endogenous GH pulsatility and insulin sensitivity in healthy men.J Clin Endocrinol MetabInna praca2011
Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data.J Clin Endocrinol MetabInna praca2010
Tesamorelin update.BETAInna praca2010
The next generation of human growth hormone. How Serostim and tesamorelin measure up.Posit AwareInna praca2008
Tesamorelin for fat accumulation. 52-week effects and safety of tesamorelin (growth hormone releasing factor) in HIV patients with fat accumulation.Posit AwareInna praca2008
Side effects and complications. Tesamorelin--results from Phase III.TreatmentUpdateInna praca2007
Side effects and complications. Clinical trials of tesamorelin in Canada.TreatmentUpdateInna praca2007

Te prace znaleźliśmy automatycznie w bazie PubMed. Redakcja jeszcze ich nie przeczytała i nie wpływają na żadną ocenę. Tytuły są w oryginale. W każdej grupie pokazujemy najnowsze prace do ustalonego limitu. Pełną listę ma PubMed.

Otwórz w PubMed

Zarejestrowane badania na ludziach (22)

BadaniaEtapStatusLiczba uczestnikówAktualizacja
Body Composition and Adipose Tissue in HIVEtap 4Przerwane62026-05-19
Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIVEtap 2Szuka uczestników1002026-05-19
Tesamorelin for Reduction of Liver Fat in Adults With Fatty Liver Disease (Mock Study)Etap 2Szuka uczestników1202026-03-19
Phase II Trial of Tesamorelin for Cognition in Aging HIV-Infected PersonsEtap 2Zakończone732026-03-12
Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular RiskEtap 2Zakończone512025-11-20
Tesamorelin to Improve Functional Outcomes After Peripheral Nerve InjuryEtap 2Szuka uczestników362025-11-12
TH9507 Extension Study in Patients With HIV-Associated LipodystrophyEtap 3Zakończone2632022-09-30
Efficacy and Safety Study of Tesamorelin in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Muscle WastingEtap 2Przerwane32022-03-18
Tesamorelin Effects on Liver Fat and Histology in HIV–Zakończone612020-01-27
Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current InsomniaEtap 2Wycofane02019-11-19
The Effect of Growth Hormone Releasing Hormone on Cognitive Function in Individuals With Mild Cognitive ImpairmentEtap 1Zakończone222019-11-04
Long-term Observational Study in HIV Subjects Exposed to EGRIFTA®–Przerwane3912018-09-11
Diabetic Retinopathy in HIV Subjects Treated With EGRIFTA®Etap 4Przerwane1292018-09-11
Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are ObeseEtap 2Zakończone602017-12-13
Effects of Growth Hormone Releasing Hormone in HIV–Zakończone542017-10-30
Egrifta Replacement and Sleep Disordered Breathing–Wycofane02017-03-03
Abdominal Obesity, Cardiovascular Inflammation, and Effects of Growth Hormone Releasing Hormone Analogue–Wycofane02014-01-24
SMART: Somatotrophics, Memory, and Aging Research TrialEtap 2Zakończone1512013-12-19
Pharmacokinetic and Pharmacodynamic Study of TH9507, a Growth Hormone-Releasing Factor Analog, in HIV Positive PatientsEtap 1Zakończone182013-12-16
TH9507 in Patients With HIV-Associated LipodystrophyEtap 3Zakończone4122013-11-27
Effect of Short Term Growth Hormone Releasing Hormone in Healthy Men–Zakończone152011-04-19
Safety Study of TH9507 in Subjects With Stable, Type 2 DiabetesEtap 2Zakończone552010-12-21