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The US health department published a draft policy under which it would not act against pharmacies that make BPC-157 on a prescription for a named patient, until the FDA decides by rule. It is still not an approved medicine.
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Vitamin B12

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Scientific papers

StudiesKind of studyYear
Vitamin B12 supplementation for growth, development, and cognition in children.Cochrane Database Syst RevPooled analysis2026
Acupoint injection increases the efficacy of vitamin B12 for diabetic neuropathy: a meta-analysis and trial sequential analysis.Eur J Clin NutrPooled analysis2026
Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis.Ir J Med SciPooled analysis2024
Comparative Efficacy of Intranasal, Intramuscular, and Intravenous Vitamin B12 Therapy for Hematological Recovery in Vitamin B12 Deficiency Anemia: A Randomized Controlled Trial.Am J HematolRandom groups2026
Clinical safety of ultra-high-dose methylcobalamin in patients with amyotrophic lateral sclerosis: Open-label extension of a phase 2/3 randomized controlled study.J Neurol SciRandom groups2026
Effects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial.J Orthop Surg ResRandom groups2024
Parenteral vs Oral Vitamin B12 in Children With Nutritional Macrocytic Anemia: A Randomized Controlled Trial.Indian PediatrRandom groups2022
Efficacy and Safety of Ultrahigh-Dose Methylcobalamin in Early-Stage Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.JAMA NeurolRandom groups2022
The Efficacy of Intramuscular Injection of Vitamin B12 in the Treatment of Acute Herpetic Neuralgia-A Prospective Pilot Study.J Altern Complement MedRandom groups2021
Effect of Vitamin B12 Injection on the Vocal Performance of Professional Singers: A Randomized, Double-blind, Placebo-Controlled, Crossover Trial.JAMA Otolaryngol Head Neck SurgRandom groups2021
Local Administration of Methylcobalamin for Subacute Ophthalmic Herpetic Neuralgia: A Randomized, Phase III Clinical Trial.Pain PractRandom groups2020
Oral versus intramuscular administration of vitamin B12 for vitamin B12 deficiency in primary care: a pragmatic, randomised, non-inferiority clinical trial (OB12).BMJ OpenRandom groups2020
[JETALS: The Japanese Early-stage Trial of high dose methylcobalamin for ALS].Brain NerveRandom groups2019
Timing of folic acid/vitamin B12 supplementation and hematologic toxicity during first-line treatment of patients with nonsquamous non-small cell lung cancer using pemetrexed-based chemotherapy: The PEMVITASTART randomized trial.CancerRandom groups2019
Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study.J Neurol Neurosurg PsychiatryRandom groups2019
Early biomarker response and patient preferences to oral and intramuscular vitamin B12 substitution in primary care: a randomised parallel-group trial.Swiss Med WklyRandom groups2017
Acupuncture combined with methylcobalamin for the treatment of chemotherapy-induced peripheral neuropathy in patients with multiple myeloma.BMC CancerRandom groups2017
Local Administration of Methylcobalamin and Lidocaine for Acute Ophthalmic Herpetic Neuralgia: A Single-Center Randomized Controlled Trial.Pain PractRandom groups2016
Sublingual vitamin B12 compared to intramuscular injection in patients with type 2 diabetes treated with metformin: a randomised trial.N Z Med JRandom groups2016
Therapeutic role of Vitamin B12 in patients of chronic tinnitus: A pilot study.Noise HealthRandom groups2016
Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.Pain MedRandom groups2016
Effects of folic acid and vitamin B12 supplementation on culling rate, diseases, and reproduction in commercial dairy herds.J Dairy SciRandom groups2014
Effect of butaphosphan and cyanocobalamin on postpartum metabolism and milk production in dairy cows.AnimalRandom groups2013
A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.Pain MedRandom groups2013
Oral versus intramuscular administration of vitamin B12 for the treatment of patients with vitamin B12 deficiency: a pragmatic, randomised, multicentre, non-inferiority clinical trial undertaken in the primary healthcare setting (Project OB12).BMC Public HealthRandom groups2012
The efficacy and safety of intramuscular injections of methylcobalamin in patients with chronic nonspecific low back pain: a randomised controlled trial.Singapore Med JRandom groups2011
Pharmacokinetics of oral cyanocobalamin formulated with sodium N-[8-(2-hydroxybenzoyl)amino]caprylate (SNAC): an open-label, randomized, single-dose, parallel-group study in healthy male subjects.Clin TherRandom groups2011
Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low cobalamin levels: a randomized, open-label, parallel-group study.Clin TherRandom groups2011
An evaluation of plasma homocysteine in the assessment of vitamin B12 status of pasture-fed sheep.N Z Vet JRandom groups2010
[Effects of intervention therapy of methylcobalamin and folic acid on plasma homocysteine concentration and homocysteine thiolactonases/paraoxonase activity in patients with type 2 diabetes mellitus].Zhonghua Yi Xue Za ZhiRandom groups2007
Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study.Clin Toxicol (Phila)Random groups2006
Comparative effects of hydroxocobalamin and cyanocobalamin on plasma homocysteine concentrations in end-stage renal disease.MetabolismRandom groups2005
Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial.Arch Intern MedRandom groups2005
The effects of 'supra-physiological' vitamin B12 administration on temporary threshold shift.Int J AudiolRandom groups2004
Randomized, placebo-controlled trial of intramuscular vitamin B12 for the treatment of hyperhomocysteinaemia in dialysis patients.Intern Med JRandom groups2003
Vitamin B12 injection for preventing cobalt deficiency in lambs.Aust Vet JRandom groups2002
Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.Eur Rev Med Pharmacol SciRandom groups2000
Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations.LancetRandom groups1995
Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome.Arch Intern MedRandom groups1989
The effect of vitamin B12 on physical performance capacity.Br J NutrRandom groups1978
Pain Fluctuations of Women with Subacute Herpetic Neuralgia During Local Methylcobalamin in Combination with Lidocaine Treatment: A Single-Blinded Randomized Controlled Trial.J Pain ResNo random groups2023
The Efficacy of Oral Vitamin B12 Replacement for Nutritional Vitamin B12 Deficiency.J Pediatr Hematol OncolNo random groups2018
Phase II study of oral vitamin B12 supplementation as an alternative to intramuscular injection for patients with non-small cell lung cancer undergoing pemetrexed therapy.Cancer Chemother PharmacolNo random groups2016
Hydroxocobalamin supplementation and erythropoisis stimulating agent hyporesponsiveness in haemodialysis patients.Nephrology (Carlton)No random groups2014
The vitamin B12 absorption test, CobaSorb, identifies patients not requiring vitamin B12 injection therapy.Scand J Clin Lab InvestNo random groups2011
Cognitive and psychiatric effects of vitamin B12 replacement in dementia with low serum B12 levels: a nursing home study.Int PsychogeriatrNo random groups2009
Effect of butaphosphane and cyanocobalamin on regeneration of muscle fibres in pigs.Pol J Vet SciNo random groups2009
Measuring holotranscobalamin II, an early indicator of negative vitamin B12 balance, by radioimmunoassay in patients with ischemic cerebrovascular disease.Ann HematolNo random groups2008
Patient acceptance of intranasal cobalamin gel for vitamin B12 replacement therapy.Hawaii Med JNo random groups2006
Parenteral vitamin B12 reduces hyperhomocysteinemia in end-stage renal disease.Clin Invest MedNo random groups2001
Enteral vitamin B12 supplements reverse postgastrectomy B12 deficiency.Ann SurgNo random groups2000
Normalization of plasma vitamin B12 concentration by intranasal hydroxocobalamin in vitamin B12-deficient patients.GastroenterologyNo random groups1997
Effects of vitamin B12 on human circadian body temperature rhythm.Neurosci LettNo random groups1995
Hydroxocobalamin. V. Prolonged maintenance of high vitamin B12 blood levels following a short course of hydroxocobalamin injections.BloodNo random groups1966
Hibiscus sabdariffa increases hydroxocobalamin oral bioavailability and clinical efficacy in vitamin B12 deficiency with neurological symptoms.Fundam Clin PharmacolGroup followed over time2016
Potential role of vitamin B12 supplementation in neurological recovery after severe traumatic brain injury.NutritionCase reports2026
Pernicious Anemia Mimicking Thrombotic Thrombocytopenic Purpura in the Setting of Severe Vitamin B12 Deficiency.CureusCase reports2026
Systemic Allergic Dermatitis Induced by Intramuscular Vitamin B12 Administration.Contact DermatitisCase reports2026
Intravenous Methylcobalamin-Induced Anaphylactic Shock: A Case Report.Curr Drug SafCase reports2026
Vitamin B12 Deficiency Mimicking Thrombotic Microangiopathy: A Case of Pseudo-Thrombotic Microangiopathy.J Community Hosp Intern Med PerspectCase reports2026
Metformin-Associated Functional Vitamin B12 Deficiency Presenting as Subacute Combined Degeneration in a 57-Year-Old Man With Diabetes Mellitus.Am J Case RepCase reports2026
Combined Ultrasound-guided Perineural Vitamin B12 Injection and Pulsed Radiofrequency of C2 Dorsal Root Ganglion for Treatment of C2 Postherpetic Neuralgia: A Case Report.J Med UltrasoundCase reports2026
Vitamin B12 Deficiency Presenting as Pseudothrombotic Microangiopathy and Intestinal Pseudo-Obstruction.CureusCase reports2026
Unveiling the Pernicious Truth: A Case Report on the Rare Presentation of Severe Vitamin B12 Deficiency.CureusCase reports2026
Two Cases of Severe Food-Borne Botulism: Could High-Dose Methylcobalamin Accelerate Recovery?CureusCase reports2025
Pseudothrombotic microangiopathy resulting from severe vitamin B12 deficiency in a pediatric patient with autism: A case report.SAGE Open Med Case RepCase reports2025
Vitamin B12 deficiency in a young male with Imerslund-Gräsbeck syndrome: case report.Front PediatrCase reports2025
Multifaceted Clinical Spectrum of Vitamin B12 Deficiency - a Case Report and Literature Review.J Blood MedCase reports2025
Clinical Case of a 20-Year-Old Man With Myeloneuropathy Due to Vitamin B12 Deficiency From Nitrous Oxide Abuse: A Case Report.CureusCase reports2025
Intramuscular Vitamin B12 Treatment in Transcobalamin II Deficiency: Case Series Clinical Outcomes.Appl Clin GenetCase reports2025
Pretibial myxedema treated with intralesional tumescent drug delivery of hyaluronidase, triamcinolone, vitamin B12, and sodium bicarbonate dissolved in a tumescent epinephrine lidocaine solution.JAAD Case RepCase reports2025
Complete Immunophenotypic Reversal of Chronic Lymphocytic Leukaemia With High Dose Parenteral Methylcobalamin: A Case Report and Brief Review of Cobalamin in Cancer.Cancer Rep (Hoboken)Case reports2025
Fewer injections, less pain: Successful cyanocobalamin desensitization.Allergol Immunopathol (Madr)Case reports2025
Severe Vitamin B12 deficiency with complications in an elderly patient: a case study of pancytopenia and haemolysis.Br J Community NursCase reports2025
Vitamin B12 Deficiency-Induced Massive Schistocytosis and Hemolytic Anemia Due to Pseudo-Thrombotic Microangiopathy: A Case Report.CureusCase reports2025
Peripheral Neuropathy Secondary to a Functional Vitamin B12 Deficiency in the Setting of Erythrocytosis.CureusCase reports2025
[A case of diagnosed pernicious anemia and subacute combined degeneration of the spinal cord with abnormally elevated serum vitamin B12].Rinsho ShinkeigakuCase reports2025
Vitamin B12 Deficiency in Pernicious Anemia: A Hemolytic Anemia Mimic.CureusCase reports2025
Atypical Motor-Predominant Presentation of Subacute Combined Degeneration of Spinal Cord Due to Vitamin B12 Deficiency: A Case Report of Stroke Mimicry in the Absence of Classic Symptoms.CureusCase reports2024
Correlation Between Nitrous Oxide and Functional Vitamin B12 Deficiency Resulting in Subacute Combined Degeneration of the Spinal Cord: A Case Report.CureusCase reports2024
Microangiopathic thrombocytopenia caused by vitamin B12 deficiency responding to plasma exchange.Br J HaematolCase reports2024
Vitamin B12 responsive developmental and epileptic encephalopathy due to a novel mutation in the FUT2 gene: a case report.BMC PediatrCase reports2024
Acute Mental Disorder Caused by Vitamin B12 Deficiency Eight Years After Total Gastrectomy.CureusCase reports2024
Oral manifestations of vitamin B12 deficiency associated with pernicious anemia: A case report.Int J Surg Case RepCase reports2024
Vitamin B12 Deficiency Manifesting As Pancytopenia, Lymphadenopathy, and Fever: A Clinical Mimic of Hematologic Malignancies.CureusCase reports2024
Vitamin B12 Deficiency-Induced Neuropathy and Cognitive and Motor Impairment in the Elderly: A Case Study.Food Nutr BullCase reports2024
Vitamin B12 Deficiency in Children and Adolescents: A Case for Revised Diagnostic Parameters.Food Nutr BullCase reports2024
A Rare Cause of Vitamin B12 Deficiency in the Pediatric Age.CureusCase reports2024
Vitamin B12 deficiency presenting as progressive blindness in a 33-year-old HIV-positive female patient on Efavirenz-based regimen: case report.Pan Afr Med JCase reports2024
Vitamin B12 Deficiency Disguised As Hemolytic Anemia: A Case Presentation.CureusCase reports2024
A Case of Subacute Degeneration of the Spinal Cord Due to Vitamin B12 Deficiency Triggered by Nitrous Oxide Use.CureusCase reports2023
Vitamin B12 induced acneiform eruption.HeliyonCase reports2023
Ultrasound-Guided Perineural Vitamin B12 Injection for Brachial Plexus Injury: A Preliminary Study.Cell TransplantCase reports2023
Severe Vitamin B12 Deficiency Presenting as Pancytopenia, Hemolytic Anemia, and Paresthesia: Could Your B12 Be Any Lower?CureusCase reports2022
Pseudo-Thrombotic Microangiopathy Secondary to Vitamin B12 Deficiency.Case Rep MedCase reports2022
[Vitamin B12 deficiency in an infant child of a mother with pernicious anemia].Andes PediatrCase reports2022
Pancytopenia Due to Vitamin B12 and Folic Acid Deficiency-A Case Report.Pediatr RepCase reports2022
Functional Vitamin B12 Deficiency in Association With Nitrous Oxide Inhalation.CureusCase reports2022
Chronic Atrophic Gastritis Presenting as Hemolytic Anemia due to Severe Vitamin B12 Deficiency.Case Rep HematolCase reports2021
Recognizing Subacute Combined Degeneration in Patients With Normal Vitamin B12 Levels.CureusCase reports2021
[Severe encephalopathy and vitamin B12 deficiency: reversibility after nutritional therapy].Nutr HospCase reports2020
[Neurologic involvement due to vitamin B12 deficiency in an infant].Arch Argent PediatrCase reports2020
[Oral diagnosis of vitamin B12 deficiency due to long-term metformin treatment: a case report].Pan Afr Med JCase reports2020
Vitamin B12 Deficiency Anemia and Polyneuropathy Due to Chronic Radiation Enteritis.Intern MedCase reports2020
High-dose hydroxocobalamin achieves biochemical correction and improvement of neuropsychiatric deficits in adults with late onset cobalamin C deficiency.JIMD RepCase reports2020
Infantile Tremor Syndrome after Peroral and Intramuscular Vitamin B12 Therapy: Two Cases.Klin PadiatrCase reports2019
Reversible cutaneous silent period abnormalities in vitamin B12 deficiency: A case report.Clin Neurophysiol PractCase reports2019
[IMERSLUND-GRÄSBECK SYNDROME CONGENITAL FORM OF VITAMIN B12 DEFICIENCY ANEMIA].Georgian Med NewsCase reports2019
Psychomotor regression due to vitamin B12 deficiency.Pan Afr Med JCase reports2018
Anaphylactic Reaction to Cyanocobalamin: A Case Report.CureusCase reports2018
Subcutaneous Eikenella corrodens, Actinomyces sp., and α-Hemolytic Streptococcus Abscess of the Thigh following a Vitamin B12 Injection.Case Rep Infect DisCase reports2018
Pseudo-Thrombotic Thrombocytopenic Purpura due to Severe Vitamin B12 Deficiency.J La State Med SocCase reports2016
Cobalt-Induced Contact Urticaria Presenting as Chronic Urticaria Due to Intramuscular Vitamin B12 Injections.DermatitisCase reports2016
Nitrous oxide misuse and vitamin B12 deficiency.BMJ Case RepCase reports2016
[Intranasal cyanocobalamin; an effective and safe therapeutic alternative].Nutr HospCase reports2014
Vitamin B12-induced acneiform eruption.Cutan Ocul ToxicolCase reports2014
A patient with an inborn error of vitamin B12 metabolism (cblF) detected by newborn screening.PediatricsCase reports2013
Early treatment causes clinicoradiological reversal of myelopathy due to vitamin B12 deficiency.BMJ Case RepCase reports2013
Vitamin B12 deficiency presenting as acute ataxia.BMJ Case RepCase reports2013
Unusual association of Arnold-Chiari malformation and vitamin B12 deficiency.BMJ Case RepCase reports2012
Severe vitamin B12 deficiency in an exclusively breastfed 5-month-old Italian infant born to a mother receiving multivitamin supplementation during pregnancy.BMC PediatrCase reports2012
Involuntary movements after correction of vitamin B12 deficiency: a video-case report.Epileptic DisordCase reports2012
Subacute combined degeneration of the spinal cord despite prophylactic vitamin B12 treatment.J Clin NeurosciCase reports2012
Psychotic disorder, hypertension and seizures associated with vitamin B12 deficiency: a case report.Hum Exp ToxicolCase reports2012
Atypical presentation of vitamin B12 deficiency.Pak J Biol SciCase reports2012
[Treatment response in vitamin B12 deficiency depends on the chosen vitamin B12 preparation].Ugeskr LaegerCase reports2011
[Homozygous mutation in the intrinsic factor gene in a child with severe vitamin B12 deficiency].Ugeskr LaegerCase reports2011
Serial nerve conduction studies in vitamin B12 deficiency-associated polyneuropathy.Neurol SciCase reports2011
Vitamin B12-responsive severe leukoencephalopathy and autonomic dysfunction in a patient with "normal" serum B12 levels.J Neurol Neurosurg PsychiatryCase reports2010
Vitamin B12 optic neuropathy in autism.PediatricsCase reports2010
Hydroxocobalamin dose escalation improves metabolic control in cblC.J Inherit Metab DisCase reports2009
Sub-acute combined degeneration with an initially normal level of vitamin B12: a case report.Cases JCase reports2009
Functional vitamin B12 deficiency.Pract NeurolCase reports2009
Neurological consequences of vitamin B12 deficiency and its treatment.Pediatr Emerg CareCase reports2008
Type I immediate hypersensitivity reaction to cyanocobalamin but not hydroxycobalamin.Clin Exp DermatolCase reports2008
Chronic psychosis associated with vitamin B12 deficiency.J Assoc Physicians IndiaCase reports2008
Treatment responsive executive and behavioral dysfunction associated with Vitamin B12 deficiency.NeurocaseCase reports2008
Hyperhomocysteinemia, deep vein thrombosis and vitamin B12 deficiency in a metformin-treated diabetic patient.J Formos Med AssocCase reports2007
Seizures during treatment of Vitamin B12 deficiency.SeizureCase reports2007
[Oral treatment of vitamin B12 deficiency in subacute combined degeneration].NervenarztCase reports2006
[Reversible peripheral neuropathy induced by vitamin B12 deficiency].Neurophysiol ClinCase reports2005
Successful treatment of chronic erythema nodosum with vitamin B12.J Am Board Fam PractCase reports2005
Megaloblastic anaemia: response to Amples A and B (folic acid, vitamin B12 (Cyanocobalamin), niacin and vitamin C)--a case report.Niger J MedCase reports2005
Anaphylactic reaction after intramuscular injection of cyanocobalamin (vitamin B12): a case report.J Pak Med AssocCase reports2005
Vitamin B12 deficiency presenting with an acute reversible extrapyramidal syndrome.Neurol IndiaCase reports2004
Vitamin B12-associated localized scleroderma and its treatment.Dermatol SurgCase reports2004
Adverse reactions to vitamin B12 injections due to benzyl alcohol sensitivity: successful treatment with intranasal cyanocobalamin.AllergyCase reports2004
A case of postoperative recurrence of fibrolamellar hepatocellular carcinoma with increased vitamin B12 binding capacity in a young Japanese female.Jpn J Clin OncolCase reports2004
Posterior arm and deltoid compartment syndrome after vitamin B12 injection.OrthopedicsCase reports2004
[A case of subacute combined degeneration with normal serum vitamin B12 level].Rinsho ShinkeigakuCase reports2003
[Myelopathy due to vitamin B12 deficiency presenting as transverse myelitis].Arq NeuropsiquiatrCase reports2002
Reversible myelopathy in a 34-year-old man with vitamin B12 deficiency.Mayo Clin ProcCase reports2002
[Myelosis funicularis as a result of secondary vitamin B12 deficiency in a 9-year-old girl].Wiad LekCase reports2002
Progressive neurological deterioration and MRI changes in cblC methylmalonic acidaemia treated with hydroxocobalamin.J Inherit Metab DisCase reports1999
Syncope following intramuscular injection of hydroxocobalamin in a paraplegic patient: indication for oral administration of cyanocobalamin in spinal cord injury patients.Spinal CordCase reports1999
Ischemic strokes secondary to vitamin B12 deficiency-induced hyperhomocystinemia.NeurologyCase reports1998
Biochemical and clinical response to hydroxocobalamin versus cyanocobalamin treatment in patients with methylmalonic acidemia and homocystinuria (cblC).J PediatrCase reports1998
[A case of vitamin B12 deficiency with broad neurologic disorders and canities].No To ShinkeiCase reports1997
Vitamin B12 deficiency: underdiagnosed, overtreated?Hosp Pract (1995)Case reports1995
[Fatty tissue necrosis and oil granuloma after subcutaneous injections of vitamin B12].Tidsskr Nor LaegeforenCase reports1993
Optic neuropathy in a patient with vitamin B12 deficiency: a case report.J Med Assoc ThaiCase reports1992
[Atypical leukemia accompanied by vitamin B12 deficiency].Rinsho KetsuekiCase reports1992
Normalization of vitamin B12 absorption after ileal resection in children.J Paediatr Child HealthCase reports1992
Complete cure of urinary and faecal incontinence after intravenous vitamin B12 therapy in a patient with post-gastrectomy megaloblastic anaemia.J Intern MedCase reports1992
Reversible hyperpigmentation of skin and nails with white hair due to vitamin B12 deficiency.Arch DermatolCase reports1986
Selective vitamin B12 malabsorption without anaemia but with profound failure to thrive.Acta Paediatr ScandCase reports1985
[Agranulocytosis and impairment of liver functions terminating in death following vitamin B12 injection in pernicious anemia: report of a case].Rinsho KetsuekiCase reports1984
A case of mania secondary to vitamin B12 deficiency.Am J PsychiatryCase reports1984
[Vitamin-B12-dependent methylmalonic acidemia in twins].Monatsschr KinderheilkdCase reports1983
Comparative efficacy of vitamin B12 supplementation routes in adults with replacement indication: a systematic review.EClinicalMedicineReview of studies2026
Oral vitamin B₁₂ after total gastrectomy for gastric cancer: mapping the evidence.Gastric CancerReview of studies2026
Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis.Front PharmacolReview of studies2025
Vitamin B12 Deficiency: Common Questions and Answers.Am Fam PhysicianReview of studies2025
The Neurological Sequelae of Vitamin B12 Deficiency: A Systematic Review and Randomized Controlled Trial.CureusReview of studies2025
Desensitization for Vitamin B12 Hypersensitivity and How to Do It.BiomedicinesReview of studies2025
Lack of Clinical Evidence Regarding the Guidelines for Vitamin B12 Deficiency: An Analysis From Literature and Recommendations From Clinical Practice.Food Nutr BullReview of studies2024
Etiology, Clinical Manifestations, Diagnosis, and Treatment of Cobalamin (Vitamin B12) Deficiency.CureusReview of studies2024
Vitamin B12 in Cats: Nutrition, Metabolism, and Disease.Animals (Basel)Review of studies2023
Metformin-Induced Vitamin B12 Deficiency among Type 2 Diabetes Mellitus' Patients: A Systematic Review.Curr Diabetes RevReview of studies2023
Role of vitamin B12 in treating recurrent aphthous stomatitis: A review.Int J Vitam Nutr ResReview of studies2022
Inherited and acquired vitamin B12 deficiencies: Which administration route to choose for supplementation?Front PharmacolReview of studies2022
Metformin-induced vitamin B12 deficiency can cause or worsen distal symmetrical, autonomic and cardiac neuropathy in the patient with diabetes.Diabetes Obes MetabReview of studies2022
Current Nanocarrier Strategies Improve Vitamin B12 Pharmacokinetics, Ameliorate Patients' Lives, and Reduce Costs.Nanomaterials (Basel)Review of studies2021
State of the art review: oral and nasal vitamin B12 therapy in the elderly.QJMReview of studies2020
Efficacy and tolerability of a fixed dose combination of cortex phospholipid liposomes and cyanocobalamin for intramuscular use in peripheral neuropathies.Minerva MedReview of studies2019
Oral Vitamin B12 Replacement for the Treatment of Pernicious Anemia.Front Med (Lausanne)Review of studies2016
Vitamin B12 deficiency - A 21st century perspective .Clin Med (Lond)Review of studies2015
A review of vitamin B12 in dermatology.Am J Clin DermatolReview of studies2015
Vitamin B12 intramuscular injections versus oral supplements: a budget impact analysis.Ont Health Technol Assess SerReview of studies2013
Vitamin B12 and cognitive function: an evidence-based analysis.Ont Health Technol Assess SerReview of studies2013
Vitamin B12 deficiency in patients undergoing bariatric surgery: preventive strategies and key recommendations.Surg Obes Relat DisReview of studies2013
Efficacy of oral cobalamin (vitamin B12) therapy.Expert Opin PharmacotherReview of studies2010
Oral or intramuscular vitamin B12?Drug Ther BullReview of studies2009
Traveling the vitamin B12 pathway: oral delivery of protein and peptide drugs.Angew Chem Int Ed EnglReview of studies2009
Update on oral cyanocobalamin (vitamin B12) treatment in elderly patients.Drugs AgingReview of studies2008
Diagnosis and treatment of vitamin B12 deficiency--an update.HaematologicaReview of studies2006
Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency: a systematic review of randomized controlled trials.Fam PractReview of studies2006
Is oral vitamin B12 as effective as intramuscular injection?Am Fam PhysicianReview of studies2006
Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency.Cochrane Database Syst RevReview of studies2005
Use of vitamin B12 conjugates to deliver protein drugs by the oral route.Crit Rev Ther Drug Carrier SystReview of studies1998
An update of vitamin B12 metabolism and deficiency states.J Fam PractReview of studies1995
Diagnosing vitamin B12 deficiency, a common geriatric disorder.GeriatricsReview of studies1988
PMVE/MA-based microneedle patches for rapid transdermal delivery of vitamin B12: fabrication and evaluation.Drug Deliv Transl ResIn animals2026
Amelioration of postpartum hyperketonemia using amino acids, cyanocobalamin, inositol, α-lipoic acid, or monensin during the transition period of dairy cows.J Dairy SciIn animals2026
Vitamin B12 Supports Skeletal Muscle Oxidative Phosphorylation Capacity in Male Mice.J NutrIn animals2026
Cyanocobalamin (vitamin B12) ameliorates lipopolysaccharide-induced systemic and lung inflammation in rats.Sci RepIn animals2025
Ameliorative effect of folic acid and vitamin B12 against Ivermectin-induced hepatotoxicity, renal toxicity, oxidative stress and immunohistochemical changes in male albino rats.Sci RepIn animals2025
Cyanocobalamin-loaded dissolving microneedles for enhanced transdermal delivery: development, characterization, and pharmacokinetic evaluation.Biomed MicrodevicesIn animals2025
Pharmacokinetic profiles of methylcobalamin in rats after multiple administration routes by a simple LC-MS/MS assay with a small volume of plasma.J Pharmacol Toxicol MethodsIn animals2024
One-carbon metabolite supplementation increases vitamin B12, folate, and methionine cycle metabolites in beef heifers and fetuses in an energy dependent manner at day 63 of gestation.J Anim SciIn animals2024
Evaluation of the Regeneration Effects of Systemically Applied Methylprednisolone and Vitamin B12 on Mental Nerve Crush Injury.Turk NeurosurgIn animals2024
Cyanocobalamin promotes muscle development through the TGF-β signaling pathway.Food FunctIn animals2022
Aspects of transition cow metabolomics-Part I: Effects of a metaphylactic butaphosphan and cyanocobalamin treatment on the metabolome in liver, blood, and urine in cows with different liver metabotypes.J Dairy SciIn animals2021
Cyanocobalamin and/or calcitriol mitigate renal damage-mediated by tamoxifen in rats: Implication of caspase-3/NF-κB signaling pathways.Life SciIn animals2021
A pilot study comparing the pharmacokinetics of injectable cyanocobalamin and hydroxocobalamin associated with a trace mineral injection in cattle.J Vet Pharmacol TherIn animals2021
Efficacy of intramuscular hydroxocobalamin supplementation in cats with cobalamin deficiency and gastrointestinal disease.J Vet Intern MedIn animals2020
Acute vitamin B12 supplementation evokes antidepressant response and alters Ntrk-2.NeuropharmacologyIn animals2020
Modest and variable efficacy of pre-exposure hydroxocobalamin and dicobalt edetate in a porcine model of acute cyanide salt poisoning.Clin Toxicol (Phila)In animals2020
Rapidly dissolving bilayer microneedle arrays - A minimally invasive transdermal drug delivery system for vitamin B12.Int J PharmIn animals2019
Added dietary cobalt or vitamin B12, or injecting vitamin B12 does not improve performance or indicators of ketosis in pre- and post-partum Holstein-Friesian dairy cows.AnimalIn animals2019
Vitamin B12 buccoadhesive tablets: auspicious non-invasive substitute for intra muscular injection: formulation, in vitro and in vivo appraisal.Drug Dev Ind PharmIn animals2019
Folate/Vitamin B12 Supplementation Combats Oxidative Stress-Associated Carcinogenesis in a Rat Model of Colon Cancer.Nutr CancerIn animals2019
Investigation of Receptor-Mediated Cyanocobalamin (Vitamin B12) Transport across the Inner Blood-Retinal Barrier Using Fluorescence-Labeled Cyanocobalamin.Mol PharmIn animals2018
Prospective long-term evaluation of parenteral hydroxocobalamin supplementation in juvenile beagles with selective intestinal cobalamin malabsorption (Imerslund-Gräsbeck syndrome).J Vet Intern MedIn animals2018
Comparative study of the tissue distribution of equimolar repeated doses of hydroxocobalamin and cobalt chloride in the rats.Ann Biol Clin (Paris)In animals2018
C. elegans MRP-5 Exports Vitamin B12 from Mother to Offspring to Support Embryonic Development.Cell RepIn animals2018
Effects of Cobalamin (Vitamin B12) on Gentamicin Induced Nephrotoxicity in Rat.Drug Res (Stuttg)In animals2017
Vitamin B12-Loaded Buccoadhesive Films as a Noninvasive Supplement in Vitamin B12 Deficiency: In Vitro Evaluation and In Vivo Comparative Study With Intramuscular Injection.J Pharm SciIn animals2017
EXPRESS: Methylcobalamin ameliorates neuropathic pain induced by vincristine in rats: Effect on loss of peripheral nerve fibers and imbalance of cytokines in the spinal dorsal horn.Mol PainIn animals2016
Effects of butafosfan with or without cyanocobalamin on the metabolism of early lactating cows with subclinical ketosis.J Anim Physiol Anim Nutr (Berl)In animals2016
Evaluation of a Novel Tc-99m Labelled Vitamin B12 Derivative for Targeting Escherichia coli and Staphylococcus aureus In Vitro and in an Experimental Foreign-Body Infection Model.Mol Imaging BiolIn animals2015
Effects of intramuscular administration of folic acid and vitamin B12 on granulosa cells gene expression in postpartum dairy cows.J Dairy SciIn animals2015
Vitamin B12 conjugation of peptide-YY(3-36) decreases food intake compared to native peptide-YY(3-36) upon subcutaneous administration in male rats.EndocrinologyIn animals2015
High-dose hydroxocobalamin administered after H2S exposure counteracts sulfide-poisoning-induced cardiac depression in sheep.Clin Toxicol (Phila)In animals2015
Intraosseous versus intravenous infusion of hydroxocobalamin for the treatment of acute severe cyanide toxicity in a Swine model.Acad Emerg MedIn animals2014
Vitamin B12 status and the effects of vitamin B12 supplementation during the first year of life of spring calves from pasture-fed dairy herds.N Z Vet JIn animals2014
The vitamin B12 analog cobinamide is an effective hydrogen sulfide antidote in a lethal rabbit model.Clin Toxicol (Phila)In animals2014
Effect of cyanocobalamin (vitamin B12) in the induction and expression of morphine tolerance and dependence in mice.Drug Res (Stuttg)In animals2014
Systemic and local peripheral injections of vitamin B12 suppressed orofacial nociception induced by formalin in rats.Drug Res (Stuttg)In animals2014
Metformin increases liver accumulation of vitamin B12 - an experimental study in rats.BiochimieIn animals2013
Effects of cobalt supplementation and vitamin B12 injections on lactation performance and metabolism of Holstein dairy cows.J Dairy SciIn animals2013
Lack of production response in grazing dairy cows supplemented with long-acting injectable vitamin B12.N Z Vet JIn animals2012
Bioavailability of vitamin B₁₂ in cows' milk.Br J NutrIn animals2012
First report about the mode of action of combined butafosfan and cyanocobalamin on hepatic metabolism in nonketotic early lactating cows.J Dairy SciIn animals2011
Effect of multiple intravenous injections of butaphosphan and cyanocobalamin on the metabolism of periparturient dairy cows.J Dairy SciIn animals2010
The effect of injectable butaphosphan and cyanocobalamin on postpartum serum beta-hydroxybutyrate, calcium, and phosphorus concentrations in dairy cattle.J Dairy SciIn animals2010
Influence of methionine supply on the response of lactational performance of dairy cows to supplementary folic acid and vitamin B12.J Dairy SciIn animals2009
Vitamin B12 absorption and metabolism in milk-fed lambs.N Z Vet JIn animals2009
Effects of supplements of folic acid, vitamin B12, and rumen-protected methionine on whole body metabolism of methionine and glucose in lactating dairy cows.J Dairy SciIn animals2009
Dose response effects of long-acting injectable vitamin B12 plus selenium (Se) on the vitamin B12 and Se status of ewes and their lambs.N Z Vet JIn animals2006
Thiamine, pyridoxine, cyanocobalamin and their combination inhibit thermal, but not mechanical hyperalgesia in rats with primary sensory neuron injury.PainIn animals2005
Effects of intramuscular injections of vitamin B12 on lactation performance of dairy cows fed dietary supplements of folic acid and rumen-protected methionine.J Dairy SciIn animals2005
Pharmacokinetics of high doses of cyanocobalamin administered by intravenous injection for 26 weeks in rats.Clin Exp Pharmacol PhysiolIn animals2005
Diversity in rat tissue accumulation of vitamin B12 supports a distinct role for the kidney in vitamin B12 homeostasis.Nephrol Dial TransplantIn animals2003
Minimally invasive lymphatic mapping using fluorescently labeled vitamin B12.J Surg ResIn animals2003
Methylcobalamin as antagonist to transient ototoxic action of gentamicin.Acta OtolaryngolIn animals2001
Methylcobalamin attenuates the hypoxia/hypoglycemia- or glutamate-induced reduction in hippocampal fiber spikes in vitro.Eur J PharmacolIn a lab dish1995
Effect of vitamin B12 status on performance of the lactating ewe and gluconeogenesis from propionate.J Dairy SciIn a lab dish1983
Changes in circulating transcobalamin II after injection of cyanocobalamin.N Engl J MedIn a lab dish1977
Quantitative aspects of the excretion of radioactive and microbiologically active material in urine after parenteral hydroxocobalamin.J Clin PatholIn a lab dish1965
Vitamin B12 replacement strategies: a Brazilian delphi consensus.EClinicalMedicineOther paper2026
Oral Cyanocobalamin Treatment in Infants Under 1 Year With Nutritional Vitamin B12 Deficiency: A Retrospective Comparison of 500 and 1000 µg Dose Regimens.J Pediatr Hematol OncolOther paper2026
Vitamin B12 deficiency in an infant secondary to nutritional deficiency and an inadequate maternal diet.JPGN RepOther paper2026
Pilot Newborn Screening for Vitamin B12 Deficiency in the Czech Republic: Results and Detailed Studies on Identified Babies and Their Mothers.Int J Neonatal ScreenOther paper2026
Clinical Outcomes and Correlation With Biochemical Control in Hydroxocobalamin-Treated Patients With Early-Onset Cobalamin C Disease.JIMD RepOther paper2026
Sublingual methylcobalamin treatment in infants with prolonged jaundice due to vitamin B12 deficiency.Front PediatrOther paper2026
Intramuscular Cyanocobalamin Treatment in Patients with Corpus Atrophic Gastritis and Vitamin B12 Deficiency: Efficacy and Predictors of Increased Requirement-A Monocentric Longitudinal Real-Life Cohort Study.NutrientsOther paper2026
Comparison of Sublingual and Intramuscular Vitamin B12 in Children With Nutritional Vitamin B12 Deficiency Megaloblastic Anemia.CureusOther paper2026
Hippophae rhamnoides: Way to Ameliorate Depressive Augury by Cyanocobalamin.Curr Drug Discov TechnolOther paper2026
Protective effects of vitamin B12 against LPS-induced cognitive impairment through modulation of neuroinflammation, oxidative stress, and cholinergic dysfunction.Iran J Basic Med SciOther paper2026
Vitamin B12 injection plus traditional Chinese medicine techniques for meralgia paresthetica: a randomized controlled trial.Front Med (Lausanne)Other paper2025
Evaluation of outcomes for patients with nitrous oxide-related myeloneuropathy treated with self-injection of hydroxocobalamin versus nurse-led injections on an ambulatory care pathway.BMJ Neurol OpenOther paper2025
Vitamin B12 supports skeletal muscle oxidative phosphorylation capacity in male mice.bioRxivOther paper2025
The Prevalence of Vitamin B12, Hemoglobin, and Ferritin Deficiency in Patients with Morbid Obesity and Changes in their Blood Levels after Bariatric Surgery.Int J Prev MedOther paper2025
Green and white analytical approach for parallel quantification of gabapentin and methylcobalamin in medicinal products using inventive RP-HPLC technique.Sci RepOther paper2025
Rapid Improvement of Hyperpigmentation, Growth, and Developmental Milestones With High-Dose Hydroxocobalamin, Betaine, and Folinic Acid Treatment: The First Patient With Cobalamin G Deficiency in Taiwan.JIMD RepOther paper2025
Evaluation of a New Sublingual Methylcobalamin Dosage Regimen for Childhood Vitamin B12 Deficiency.Children (Basel)Other paper2025
Vitamin B12 deficiency in newborns: impact on individual's health status and healthcare costs.Clin Chem Lab MedOther paper2025
Clinical and Hematological Characteristics of Vitamin B12 Deficiency and Evaluation of the Therapeutic Response to Vitamin B12 Supplementation.CureusOther paper2024
Vitamin B12 Deficiency in Thrombotic Thrombocytopenic Purpura-Like Cases.Eur J Case Rep Intern MedOther paper2024
Oral vitamin B12 supplementation in pernicious anemia: a prospective cohort study.Am J Clin NutrOther paper2024
Benefits of Combining Antiepileptic Drugs with Vitamin B12 on Redox Balance: Penicillin-Induced Experimental Epilepsy Model.Neuropsychiatr Dis TreatOther paper2024
The MMACHC variant c.158T>C: Mild clinical and biochemical phenotypes and marked hydroxocobalamin response in cblC patients.Mol Genet MetabOther paper2024
Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.Brain CircOther paper2024
Effect of Vitamin B12 Replacement Intervals on Clinical Symptoms and Laboratory Findings in Gastric Cancer Patients after Total Gastrectomy.Cancers (Basel)Other paper2023
Uncovering the neuroprotective effect of vitamin B12 in pneumococcal meningitis: insights into its pleiotropic mode of action at the transcriptional level.Front ImmunolOther paper2023
The Effect of High-Dose Methyl Vitamin B12 Therapy on Epileptogenesis in Rats: An In Vivo Study.CureusOther paper2023
Protective role of vitamin B12 on acetic acid induced colitis in rats.Turk J SurgOther paper2023
Therapeutic Potential of Zeolites/Vitamin B12 Nanocomposite on Complete Freund's Adjuvant-Induced Arthritis as a Bone Disorder: In Vivo Study and Bio-Molecular Investigations.Pharmaceuticals (Basel)Other paper2023
Acquired Vitamin B12 Deficiency in Newborns: Positive Impact on Newborn Health through Early Detection.NutrientsOther paper2022
Combination of high performance liquid chromatography and flame atomic absorption spectrophotometry using a novel nebulizer interface supported T shaped slotted quartz tube for the determination of Vitamin B12.J Pharm Biomed AnalOther paper2022
A Hospital Based Study to Access the Usefulness of Using the Combination Regime of the Ferric Carboxy Maltose, Vitamin B12 and Folic Acid as a Treatment of Severe Anemia among Pregnant Women in a Rural Tribal Community of South Gujarat.Indian J Community MedOther paper2022
Hydroxocobalamin: An Effective Treatment for Flushing and Persistent Erythema in Rosacea.J Clin Aesthet DermatolOther paper2022
Oral vs. Intramuscular Vitamin B12 for Treating Vitamin B12 Deficiency.Am Fam PhysicianOther paper2022
Sublingual methylcobalamin treatment is as effective as intramuscular and peroral cyanocobalamin in children age 0-3 years.HematologyOther paper2021
Testing and Prescribing Vitamin B12 in Swiss General Practice: A Survey among Physicians.NutrientsOther paper2021
Subcutaneous vitamin B12 administration using a portable infusion pump in cobalamin-related remethylation disorders: a gentle and easy to use alternative to intramuscular injections.Orphanet J Rare DisOther paper2021
Plasma Vitamin B12 Levels, High-Dose Vitamin B12 Treatment, and Risk of Dementia.J Alzheimers DisOther paper2021
Comparison of Sublingual and Intramuscular Administration of Vitamin B12 for the Treatment of Vitamin B12 Deficiency in Children.Rev Invest ClinOther paper2020
Atrophic glossitis in pernicious anemia patients can be treated to normal in two weeks by intramuscular injection of vitamin B12.J Dent SciOther paper2020
Various Neurological Symptoms with Vitamin B12 Deficiency and Posttreatment Evaluation.J Pediatr NeurosciOther paper2020
Preparation of Lotus Root-Type Monolithic-Activated Carbons with an Hierarchical Pore Structure from Rice Husks and Their Adsorption of Vitamin B12.ACS OmegaOther paper2019
Prevalence of Inappropriateness of Parenteral Vitamin B12 Administration in Ontario, Canada.JAMA Intern MedOther paper2019
Open Trial of Vitamin B12 Nasal Drops in Adults With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Comparison of Responders and Non-Responders.Front PharmacolOther paper2019
Parenteral hydroxocobalamin dose intensification in five patients with different types of early onset intracellular cobalamin defects: Clinical and biochemical responses.JIMD RepOther paper2019
Comparison of sublingual vs. intramuscular administration of vitamin B12 for the treatment of patients with vitamin B12 deficiency.Drug Deliv Transl ResOther paper2019
Physicochemical Stability of Extemporaneously Prepared Methylcobalamin Injections in the Presence and Absence of Preservative and the Impact of Light Exposure.Int J Pharm CompdOther paper2019
Liquid Chromatography Method for the Simultaneous Quantification of Biotin and Vitamin B12 in Vitamin B Supplements.J AOAC IntOther paper2019
The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.Clin Nutr ResOther paper2019
Correlation of Vitamin D3 (Calcitriol) Serum Concentrations with Vitamin B12 and Folic Acid in Women Undergoing in vitro Fertilisation/Intracytoplasmatic Sperm Injection.Gynecol Obstet InvestOther paper2019
The Japanese Early-Stage Trial of High-Dose Methylcobalamin for Amyotrophic Lateral Sclerosis (JETALS): Protocol for a Randomized Controlled Trial.JMIR Res ProtocOther paper2018
[Injections to treat vitamin B12 deficiency are unnecessary].Tidsskr Nor LaegeforenOther paper2018
Comparison of the efficacy of parenteral and oral treatment for nutritional vitamin B12 deficiency in children.HematologyOther paper2018
Systematic Review and Pragmatic Clinical Approach to Oral and Nasal Vitamin B12 (Cobalamin) Treatment in Patients with Vitamin B12 Deficiency Related to Gastrointestinal Disorders.J Clin MedOther paper2018
A randomized, open labeled study comparing the serum levels of cobalamin after three doses of 500 mcg vs. a single dose methylcobalamin of 1500 mcg in patients with peripheral neuropathy.Korean J PainOther paper2018
Voluntary fortification is ineffective to maintain the vitamin B12 and folate status of older Irish adults: evidence from the Irish Longitudinal Study on Ageing (TILDA).Br J NutrOther paper2018
A vitamin B12 conjugate of exendin-4 improves glucose tolerance without associated nausea or hypophagia in rodents.Diabetes Obes MetabOther paper2018
Efficacy of Long-Term Oral Vitamin B12 Supplementation after Total Gastrectomy: Results from a Prospective Study.GE Port J GastroenterolOther paper2018

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Registered studies in people (37)

StudiesStageStatusPeople taking partUpdated
Combination Gerotherapeutic Interventions for Healthspan ImprovementStage 3Finished262026-10-30
Effect of Vitamin D and Folic Acid on Mild Cognitive Impairment–Finished3802026-10-30
Vitamin B12 Supplementation During Pregnancy on Cognitive DevelopmentStage 2, Stage 3Running, no new people8002026-04-27
A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome–Looking for people842026-04-23
Efficiency of a Composite Personalised Care on Functional Outcome in Early PsychosisStage 3Looking for people5002026-04-20
Pre- and Post-Treatment Investigation of B12 and Folic Acid (Folate) Levels in Patients Receiving Antiepileptic (Anticonvulsant) Treatment for Fibromyalgia: Retrospective Study–Finished1042026-01-26
Effects of Vitamin B12 and Natural Orange Extract, and Their Combination on Physical and Mental Performance–By invitation202026-01-14
Multicenter RCT of Eye-Brain Imaging in Diabetes Neurovascular CouplingStage 2Not started1602025-09-26
Prednisolone and Vitamin B1/6/12 in Patients With Post-Covid-SyndromeStage 3Finished3212025-04-01
Evaluation of MicroRNAs and Vitamin B12 Expression in Subjects with Neurologic Symptoms of Depression, Anxiety and Fatigue in Long COVID-19–Looking for people202025-03-07
Developmental Origins of Mental Health Disorders–Finished3862025-02-21
Effect of Methylcobalamin and Cyanocobalamin Consumption on Vitamin B12 Nutritional Status–Looking for people542024-10-30
Effect of a New Formulation of Vitamin B12 on Physical and Mental–Looking for people182024-10-15
An Exploratory Investigation of a B12 Vitamin to Increase Energy and Focus–Finished382024-08-23
Vitamin B12 vs B3 for Nerve Regeneration and Functional Recovery After Pediatric Traumatic Brain InjuryStage 3Finished3002023-07-24
Interaction of Cobalamin Status With Nitrous Oxide in Relation to Postoperative Cognitive Changes in the Elderly–Finished4442022-08-08
Factors Predicting Erythropoietin Responsiveness in Children on Hemodialysis at Sohag University Hospital–Unknown502022-04-05
Randomized Trial of Vitamin B12 in Pregnant Indian Women–Finished3662020-07-28
Effect of an Antioxidants Mix on Cognitive Performance and Well Being: The Bacopa, Licopene, Astaxantina, Vitamin B12–Finished802020-07-27
Effects of Vitamin B12 Treatment in SingersEarly stage 1Finished202019-04-09
To Evaluate the Effect of Reveratrol,Folic Acid, Vitamin D, Vitamin B12 and B6 in Male Infertility–Unknown202019-03-06
Recombinant Bovine Basic Fibroblast Growth Factor for the Treatment of Radiation Induced Oral MucositisStage 2Unknown902018-12-27
Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)Stage 1Finished382018-06-26
Effect of Vitamin B on Plasma Neurofilament Light Protein (NFL) in HIV-infected Individuals With Increased Plasma HomocysteineStage 2Unknown602018-01-02
Study of the Association of Muscle Strength, Balance and Other Factors With Vitamin Levels Among Elderly Diabetics–Finished562017-12-19
Lume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLCStage 3Finished7182017-02-02
Vitamin Supplementation After Bariatric Surgery–Unknown302016-09-30
Pemetrexed as Second-Line Therapy in Treating Patients With Hormone Refractory Prostate CancerStage 2Finished492016-07-29
Efficacy and Safety of FORRAD® for the Management of Radiation-induced Mucositis in Patients With Nasopharyngeal Carcinoma Receiving IMRTStage 2Unknown902016-04-12
Impact of Vitamin B12 Replacement on Epogen Dosing and Improvement of Quality of Life in Hemodialysis Patients–Finished1322014-09-08
Vitamin B12 Supplementation During PregnancyStage 2, Stage 3Finished1202014-04-03
Neuropathic Pain ManagementStage 3Finished1042014-02-13
A Study for Patients With Recurrent or Metastatic Squamous Cell Head and Neck CancerStage 2Finished662013-09-18
Beyond Ageing Project: A Study for the Prevention of DepressionStage 2Finished9092011-09-13
Vitamin B12 and Folic Acid Supplementation for Preventing Fractures in Elderly PeopleStage 1Unknown30002011-08-25
Plasma Holotranscobalamin as Compared to Plasma Cobalamins for Assessment of Vitamin B12 Absorption–Finished782006-03-23
Oral Vitamin B12 Supplementation and Cognitive Performance in Elderly People–Finished1652005-06-24