| Insulin-like growth factor I receptor expression and function in fibroblasts from two patients with deletion of the distal long arm of chromosome 15.J Clin Endocrinol Metab | Case reports | 1995 |
| The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.Front Endocrinol (Lausanne) | Review of studies | 2026 |
| The role of insulin-like growth factors in small intestinal cell growth and development.Horm Metab Res | Review of studies | 1999 |
| Revolutionary decellularized Alstroemeria stem-based nerve conduit integrated with GelMA and controlled IGF-1 LR3 release for enhanced rat sciatic nerve regeneration.Int J Biol Macromol | In animals | 2025 |
| Attenuated glucose-stimulated insulin secretion during an acute IGF-1 LR3 infusion into fetal sheep does not persist in isolated islets.J Dev Orig Health Dis | In animals | 2023 |
| N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling.Int J Mol Sci | In animals | 2022 |
| Reduced glucose-stimulated insulin secretion following a 1-wk IGF-1 infusion in late gestation fetal sheep is due to an intrinsic islet defect.Am J Physiol Endocrinol Metab | In animals | 2021 |
| IGF-1 infusion to fetal sheep increases organ growth but not by stimulating nutrient transfer to the fetus.Am J Physiol Endocrinol Metab | In animals | 2021 |
| Coronary vascular growth matches IGF-1-stimulated cardiac growth in fetal sheep.FASEB J | In animals | 2020 |
| Inhibition of activin-like kinase 4/5 attenuates cancer cachexia associated muscle wasting.Sci Rep | In animals | 2019 |
| Epidermal growth factor receptor is required for estradiol-stimulated bovine satellite cell proliferation.Domest Anim Endocrinol | In animals | 2014 |
| Na+ transport across rumen epithelium of hay-fed sheep is acutely stimulated by the peptide IGF-1 in vitro.Exp Physiol | In animals | 2012 |
| Enhancement of maternal lactation performance during prolonged lactation in the mouse by mouse GH and long-R3-IGF-I is linked to changes in mammary signaling and gene expression.J Endocrinol | In animals | 2008 |
| Localization of insulin-like growth factor (IGFBP)-3 in cultured porcine embryonic myogenic cells before and after TGF-beta1 treatment.Domest Anim Endocrinol | In animals | 2007 |
| Leptin in the bovine corpus luteum: receptor expression and effects on progesterone production.Mol Reprod Dev | In animals | 2007 |
| Insulin-like growth factor-binding protein-3 inhibition of prostate cancer growth involves suppression of angiogenesis.Oncogene | In animals | 2007 |
| Effect of constitutive expression of porcine IGFBP-3 on proliferation and differentiation of L6 myogenic cells.Domest Anim Endocrinol | In animals | 2006 |
| The local expression and abundance of insulin-like growth factor (IGF) binding proteins in skeletal muscle are regulated by age and gender but not local IGF-I in vivo.Endocrinology | In animals | 2005 |
| Production of recombinant porcine IGF-binding protein-5 and its effect on proliferation of porcine embryonic myoblast cultures in the presence and absence of IGF-I and Long-R3-IGF-I.J Endocrinol | In animals | 2005 |
| Effect of recombinant porcine IGFBP-3 on IGF-I and long-R3-IGF-I-stimulated proliferation and differentiation of L6 myogenic cells.J Cell Physiol | In animals | 2004 |
| Regulation of insulin-like growth factor (IGF)-binding protein expression by growth factors and cytokines alters IGF-mediated proliferation of postnatal lung fibroblasts.Exp Lung Res | In animals | 2004 |
| Extracellular signal-regulated kinase and phosphoinositol-3 kinase mediate IGF-1 induced proliferation of fetal sheep cardiomyocytes.Am J Physiol Regul Integr Comp Physiol | In animals | 2003 |
| Interaction of bovine granulosa and theca cells in a novel serum-free co-culture system.Reproduction | In animals | 2003 |
| Paracrine effects of oocyte secreted factors and stem cell factor on porcine granulosa and theca cells in vitro.Reprod Biol Endocrinol | In animals | 2003 |
| Oocyte-mediated suppression of follicle-stimulating hormone- and insulin-like growth factor-induced secretion of steroids and inhibin-related proteins by bovine granulosa cells in vitro: possible role of transforming growth factor alpha.Biol Reprod | In animals | 2003 |
| Effect of recombinant porcine IGF-binding protein-3 on proliferation of embryonic porcine myogenic cell cultures in the presence and absence of IGF-I.J Endocrinol | In animals | 2003 |
| Insulin-like growth factor-I and analogues increase growth in artificially-reared neonatal pigs.Br J Nutr | In animals | 2002 |
| Effects of insulin-like growth factor-I and its analogue, long-R3-IGF-I, on intestinal absorption of 3-O-methyl-D-glucose are less pronounced than gut mucosal growth responses.Growth Factors | In animals | 2002 |
| Steroidogenesis in bovine granulosa cells: the effect of short-term changes in dietary intake.Reproduction | In animals | 2002 |
| Modulatory effects of gonadotrophins and insulin-like growth factor on the secretion of inhibin A and progesterone by granulosa cells from chicken preovulatory (F1-F3) follicles.Reproduction | In animals | 2002 |
| Mechanisms of age-related decline in insulin-like growth factor-I dependent proteoglycan synthesis in rat intervertebral disc cells.Spine (Phila Pa 1976) | In animals | 2001 |
| Insulin-like growth factor-binding protein-5 inhibits growth and induces differentiation of mouse osteosarcoma cells.Biochem Biophys Res Commun | In animals | 2001 |
| Interactions between follicle-stimulating hormone and growth factors in modulating secretion of steroids and inhibin-related peptides by nonluteinized bovine granulosa cells.Biol Reprod | In animals | 2001 |
| Granulosa cells of the cumulus oophorus are different from mural granulosa cells in their response to gonadotrophins and IGF-I.J Endocrinol | In animals | 2001 |
| Production of tissue inhibitors of metalloproteinases (TIMPs) by pig ovarian cells in vivo and the effect of TIMP-1 on steroidogenesis in vitro.J Reprod Fertil | In animals | 2000 |
| Intramammary infusion of insulin or long R3 insulin-like growth factor-I did not increase milk protein yield in dairy cows.J Dairy Sci | In animals | 2000 |
| Differential regulation of IGF-binding proteins in rabbit costal chondrocytes by IGF-I and dexamethasone.J Endocrinol | In animals | 2000 |
| Response of isolated ruminant mammary arteries to the long R3 analogue of insulin-like growth factor I.Exp Physiol | In animals | 2000 |
| Differential regulation of pig theca cell steroidogenesis by LH, insulin-like growth factor I and granulosa cells in serum-free culture.J Reprod Fertil | In animals | 2000 |
| Novel studies on influence of gonadotropins and insulin-like growth factor-I on growth of cumulus oophorus in the rat.Endocrine | In animals | 2000 |
| Action of long(R3)-insulin-like growth factor-1 on protein metabolism in beef heifers.Domest Anim Endocrinol | In animals | 1999 |
| Cellular localization and expression of insulin-like growth factors (IGFs) and IGF binding proteins within the epiphyseal growth plate of the ovine fetus: possible functional implications.Can J Physiol Pharmacol | In animals | 1999 |
| Maintenance of oestradiol production and expression of cytochrome P450 aromatase enzyme mRNA in long-term serum-free cultures of pig granulosa cells.J Reprod Fertil | In animals | 1999 |
| Rat milk and dietary long arginine3 insulin-like growth factor I promote intestinal growth of newborn rat pups.Pediatr Res | In animals | 1998 |
| Insulin-like growth factor-1 (IGF-1) receptor-insulin receptor substrate complexes in the uterus. Altered signaling response to estradiol in the IGF-1(m/m) mouse.J Biol Chem | In animals | 1998 |
| Small intestinal morphology in eight-day-old calves fed colostrum for different durations or only milk replacer and treated with long-R3-insulin-like growth factor I and growth hormone.J Anim Sci | In animals | 1998 |
| Effects of dose of LH on androgen production and luteinization of ovine theca cells cultured in a serum-free system.J Reprod Fertil | In animals | 1998 |
| Endocrine and metabolic changes in neonatal calves in response to growth hormone and long-R3-insulin-like growth factor-I administration.Biol Neonate | In animals | 1998 |
| Long [R3] insulin-like growth factor-I reduces growth, plasma growth hormone, IGF binding protein-3 and endogenous IGF-I concentrations in pigs.J Endocrinol | In animals | 1997 |
| Interactions between follicle-stimulating hormone and growth factors in regulation of deoxyribonucleic acid synthesis in bovine granulosa cells.Biol Reprod | In animals | 1997 |
| The somatotropic axis in neonatal calves can be modulated by nutrition, growth hormone, and Long-R3-IGF-I.Am J Physiol | In animals | 1997 |
| Effects of insulin and insulin-like growth factors on proliferation of rat ovarian theca-interstitial cells.Biol Reprod | In animals | 1997 |
| Thyrotropin via cyclic AMP induces insulin receptor expression and insulin Co-stimulation of growth and amplifies insulin and insulin-like growth factor signaling pathways in dog thyroid epithelial cells.J Biol Chem | In animals | 1996 |
| Inhibition of cellular proliferation and modulation of insulin-like growth factor binding proteins by retinoids in a bovine mammary epithelial cell line.J Cell Physiol | In animals | 1996 |
| Design and characterisation of long-R3-insulin-like growth factor-I muteins which show resistance to pepsin digestion.Growth Factors | In animals | 1996 |
| Administration of insulin-like growth factor-I (IGF-I) peptides for three days stimulates proliferation of the small intestinal epithelium in rats.Gut | In animals | 1995 |
| Insulin-like growth factor binding proteins-2 and -3 stimulate growth hormone receptor binding and mitogenesis in rat osteosarcoma cells.Endocrinology | In animals | 1995 |
| Long R3 insulin-like growth factor-I (IGF-I) infusion stimulates organ growth but reduces plasma IGF-I, IGF-II and IGF binding protein concentrations in the guinea pig.J Endocrinol | In animals | 1995 |
| Effects of insulin and insulin-like growth factors on protein and energy metabolism in tumour-bearing rats.Biochem J | In animals | 1994 |
| Differential steroidogenic response of subpopulations of porcine granulosa cells to insulin-like growth factor-1 (IGF-1) or IGF-1 analogs.Biol Reprod | In animals | 1994 |
| Several insulin-like growth factor-I analogues and complexes of insulin-like growth factors-I and -II with insulin-like growth factor-binding protein-3 fail to mimic the effect of growth hormone upon lactation in the rat.J Endocrinol | In animals | 1994 |
| Effects of IGF-I bioavailability on bovine preantral follicular development in vitro.Reproduction | In a lab dish | 2007 |
| The effect of insulin-like growth factor analogs on turkey satellite cell and embryonic myoblast proliferation.Poult Sci | In a lab dish | 2001 |
| Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice.J Alzheimers Dis | Other paper | 2025 |
| Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris.Appl Microbiol Biotechnol | Other paper | 2023 |
| Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep.Front Physiol | Other paper | 2022 |
| IGF-1 has plaque-stabilizing effects in atherosclerosis by altering vascular smooth muscle cell phenotype.Am J Pathol | Other paper | 2011 |
| Detection of His-tagged Long-R³-IGF-I in a black market product.Growth Horm IGF Res | Other paper | 2010 |
| Potentiation of growth factor signaling by insulin-like growth factor-binding protein-3 in breast epithelial cells requires sphingosine kinase activity.J Biol Chem | Other paper | 2009 |
| Novel insulin-like growth factor-methotrexate covalent conjugate inhibits tumor growth in vivo at lower dosage than methotrexate alone.Transl Res | Other paper | 2009 |
| NKX3.1 activates expression of insulin-like growth factor binding protein-3 to mediate insulin-like growth factor-I signaling and cell proliferation.Cancer Res | Other paper | 2009 |
| In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417.Cancer Res | Other paper | 2006 |
| Insulin-like growth factor binding protein (IGFBP)-3 and IGFBP-5 mediate TGF-beta- and myostatin-induced suppression of proliferation in porcine embryonic myogenic cell cultures.Exp Cell Res | Other paper | 2005 |
| Insulin-like growth factor I stimulates telomerase activity in prostate cancer cells.J Clin Endocrinol Metab | Other paper | 2003 |
| Effects of a non-IGF binding mutant of IGFBP-5 on cell death in human breast cancer cells.Biochem Biophys Res Commun | Other paper | 2002 |
| Insulin-like growth factor binding protein-2 mediates the inhibition of DNA synthesis by transforming growth factor-beta in mink lung epithelial cells.J Cell Physiol | Other paper | 2002 |
| Effect of IGFBP-3 on IGF- and IGF-analogue-induced insulin-like growth factor-I receptor (IGFIR) signalling.Growth Horm IGF Res | Other paper | 2001 |
| Defect in insulin-like growth factor-1 survival mechanism in atherosclerotic plaque-derived vascular smooth muscle cells is mediated by reduced surface binding and signaling.Circ Res | Other paper | 2001 |
| Insulin-like growth factor binding protein-3 is secreted as a phosphoprotein by human breast cancer cells.Mol Cell Endocrinol | Other paper | 1999 |
| Clearance of IGFs and insulin from wounds: effect of IGF-binding protein interactions.Am J Physiol | Other paper | 1999 |
| Chemical treatment of Escherichia coli: 3. Selective extraction of a recombinant protein from cytoplasmic inclusion bodies in intact cells.Biotechnol Bioeng | Other paper | 1999 |
| Involvement of insulin-like growth factor-1 and its binding proteins in proliferation and differentiation of murine bone marrow-derived macrophage precursors.Endocrine | Other paper | 1998 |
| Effect of follicle stimulating hormone and insulin-like growth factors on proteolysis of insulin-like growth factor binding protein-4 in human granulosa cells.Mol Hum Reprod | Other paper | 1998 |
| Chemical treatment of Escherichia coli. II. Direct extraction of recombinant protein from cytoplasmic inclusion bodies in intact cells.Biotechnol Bioeng | Other paper | 1998 |
| Insulin-like growth factor binding protein-3 induces apoptosis in MCF7 breast cancer cells.Biochem Biophys Res Commun | Other paper | 1997 |
| Proteolysis of insulin-like growth factor-binding protein-3 by human skin keratinocytes in culture in comparison to that in skin interstitial fluid: the role and regulation of components of the plasmin system.J Clin Endocrinol Metab | Other paper | 1997 |
| Antiproliferative action of vitamin D-related compounds and insulin-like growth factor-binding protein 5 accumulation.J Natl Cancer Inst | Other paper | 1997 |
| Inhibition of insulin- and insulin-like growth factor-I-stimulated growth of human breast cancer cells by 1,25-dihydroxyvitamin D3 and the vitamin D3 analogue EB1089.Eur J Cancer | Other paper | 1996 |
| Regulation of insulin-like growth factor-binding protein-4 in human endometrial stromal cell cultures: evidence for ligand-induced proteolysis.J Clin Endocrinol Metab | Other paper | 1995 |
| Proteolytic degradation of insulin-like growth factor (IGF)-binding protein-3 by porcine ovarian granulosa cells in culture: regulation by IGF-I.Endocrinology | Other paper | 1994 |
| Cytokines modulate the sensitivity of human fibroblasts to stimulation with insulin-like growth factor-I (IGF-I) by altering endogenous IGF-binding protein production.J Endocrinol | Other paper | 1993 |