| Effects of glutathione- S -transferase polymorphisms on intravenous busulfan in hematopoietic stem cell transplant patients: a meta-analysis.Pharmacogenet Genomics | Pooled analysis | 2026 |
| Efficacy and safety of injectable sodium hyaluronate with vitamin C, tranexamic acid, and glutathione for pigmented dark circles.J Dermatolog Treat | Random groups | 2025 |
| Glutathione, Vitamin C, and Cysteine Use in Autistic Children With Disruptive Behavior: A Double-Blind, Placebo-Controlled Crossover Pilot Study.J Dev Behav Pediatr | Random groups | 2025 |
| Efficacy of addition of the anti-inflammatory, IV glutathione to standard ketamine IV therapy in major depressive disorder.Psychiatry Res | Random groups | 2024 |
| Early and prolonged glutathione infusion favorably impacts length of hospital stay in ST-elevation myocardial infarction patients: a subanalysis of the GSH2014 Trial.Minerva Cardiol Angiol | Random groups | 2023 |
| The effects of the oral supplementation of L-Cystine associated with reduced L-Glutathione-GSH on human skin pigmentation: a randomized, double-blinded, benchmark- and placebo-controlled clinical trial.J Cosmet Dermatol | Random groups | 2022 |
| Glutathione Infusion Before and 3 Days After Primary Angioplasty Blunts Ongoing NOX2-Mediated Inflammatory Response.J Am Heart Assoc | Random groups | 2021 |
| Combination of topical and oral glutathione as a skin-whitening agent: a double-blind randomized controlled clinical trial.Int J Dermatol | Random groups | 2021 |
| Glutathione infusion before primary percutaneous coronary intervention: a randomised controlled pilot study.BMJ Open | Random groups | 2019 |
| Clinical observation on tranexamic acid combined with reduced glutathione for the treatment of chloasma.Pak J Pharm Sci | Random groups | 2018 |
| Study of glutathione S-transferase levels in patients receiving intravenous paracetamol perioperatively: A randomized controlled trial.Indian J Gastroenterol | Random groups | 2018 |
| Whey Protein Supplementation Improves Nutritional Status, Glutathione Levels, and Immune Function in Cancer Patients: A Randomized, Double-Blind Controlled Trial.J Med Food | Random groups | 2018 |
| Glutathione-PEGylated liposomal methylprednisolone in comparison to free methylprednisolone: slow release characteristics and prolonged lymphocyte depression in a first-in-human study.Br J Clin Pharmacol | Random groups | 2018 |
| Does Rectus Sheath Block Analgesia Alter Levels of the Oxidative Stress Biomarker Glutathione Peroxidase: A Randomised Trial of Patients with Cancer and Benign Disease.Anticancer Res | Random groups | 2017 |
| [Preventive effect of mecobalamin combined with glutathione on neurotoxicity induced by FOLFOX4 chemotherapy].Zhonghua Zhong Liu Za Zhi | Random groups | 2016 |
| Effect of High-Dose Cysteine Supplementation on Erythrocyte Glutathione: A Double-Blinded, Randomized Placebo-Controlled Pilot Study in Critically Ill Neonates.JPEN J Parenter Enteral Nutr | Random groups | 2016 |
| Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study.J Dermatolog Treat | Random groups | 2012 |
| Intravenous glutathione prevents renal oxidative stress after coronary angiography more effectively than oral N-acetylcysteine.Heart Vessels | Random groups | 2011 |
| [Assessment of the protective effect of calcium-magnesium infusion and glutathione on oxaliplatin-induced neurotoxicity].Zhonghua Zhong Liu Za Zhi | Random groups | 2010 |
| Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase.Br J Clin Pharmacol | Random groups | 2009 |
| Glutamine administration in patients undergoing cardiac surgery and the influence on blood glutathione levels.Acta Anaesthesiol Scand | Random groups | 2009 |
| The effect of intravenous alanyl-glutamine supplementation on plasma glutathione levels in intensive care unit trauma patients receiving enteral nutrition: the results of a randomized controlled trial.Anesth Analg | Random groups | 2009 |
| Administration of reduced glutathione in FOLFOX4 adjuvant treatment for colorectal cancer: effect on oxaliplatin pharmacokinetics, Pt-DNA adduct formation, and neurotoxicity.Anticancer Drugs | Random groups | 2009 |
| Randomized, double-blind, pilot evaluation of intravenous glutathione in Parkinson's disease.Mov Disord | Random groups | 2009 |
| Poorly controlled type 1 diabetes is associated with altered glutathione homeostasis in adolescents: apparent resistance to N-acetylcysteine supplementation.Pediatr Diabetes | Random groups | 2008 |
| [Protective effect of reduced glutathione on multiple organ function in patient with acute pancreatitis].Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | Random groups | 2005 |
| [Enhancement of antioxidant capability of cancer patients during chemotherapy by reduced glutathione].Ai Zheng | Random groups | 2004 |
| Glutamine attenuates post-traumatic glutathione depletion in human muscle.Clin Sci (Lond) | Random groups | 2003 |
| Neuroprotective effect of reduced glutathione on oxaliplatin-based chemotherapy in advanced colorectal cancer: a randomized, double-blind, placebo-controlled trial.J Clin Oncol | Random groups | 2002 |
| Effect of glutathione infusion on leg arterial circulation, cutaneous microcirculation, and pain-free walking distance in patients with peripheral obstructive arterial disease: a randomized, double-blind, placebo-controlled trial.Mayo Clin Proc | Random groups | 2002 |
| [Effect of domestic glutathione on the alcoholic liver disease].Zhonghua Gan Zang Bing Za Zhi | Random groups | 2000 |
| Glutathione in the prevention of cisplatin induced toxicities. A prospectively randomized pilot trial in patients with head and neck cancer and non small cell lung cancer.Wien Klin Wochenschr | Random groups | 2000 |
| The effect of glutathione and N-acetylcysteine on lipoperoxidative damage in patients with early septic shock.Am J Respir Crit Care Med | Random groups | 2000 |
| Altered plasma cytokines and total glutathione levels in parenterally fed critically ill trauma patients with adjuvant recombinant human growth hormone (rhGH) therapy.Crit Care Med | Random groups | 2000 |
| Influence of reduced glutathione infusion on glucose metabolism in patients with non-insulin-dependent diabetes mellitus.Metabolism | Random groups | 1998 |
| Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: a randomized double-blind placebo-controlled trial.J Clin Oncol | Random groups | 1995 |
| Placebo-controlled, double-blind, cross-over trial of glutathione therapy in male infertility.Hum Reprod | Random groups | 1993 |
| [Usefulness of the prevention of oxygen radical damage in the critical patient using the parenteral administration of reduced glutathione in high doses].Boll Soc Ital Biol Sper | Random groups | 1992 |
| Influence of glutathione administration on the disposition of free and total platinum in patients after administration of cisplatin.Cancer Chemother Pharmacol | Random groups | 1992 |
| Glutathione (GSH) improved haemostatic and haemorheological parameters in atherosclerotic subjects.Drugs Exp Clin Res | Random groups | 1992 |
| Effect of nicardipine infusion on the release of glutathione S-transferase following halothane anaesthesia.Br J Anaesth | Random groups | 1989 |
| Protein intake affects erythrocyte glutathione synthesis in young healthy adults in a repeated-measures trial.Am J Clin Nutr | No random groups | 2024 |
| N-Acetylcysteine rapidly replenishes central nervous system glutathione measured via magnetic resonance spectroscopy in human neonates with hypoxic-ischemic encephalopathy.J Cereb Blood Flow Metab | No random groups | 2018 |
| Repeated-Dose Oral N-Acetylcysteine in Parkinson's Disease: Pharmacokinetics and Effect on Brain Glutathione and Oxidative Stress.J Clin Pharmacol | No random groups | 2018 |
| Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study.BMC Gastroenterol | No random groups | 2017 |
| An open-label, single-arm trial of the safety and efficacy of a novel preparation of glutathione as a skin-lightening agent in Filipino women.Int J Dermatol | No random groups | 2016 |
| N-Acetylcysteine boosts brain and blood glutathione in Gaucher and Parkinson diseases.Clin Neuropharmacol | No random groups | 2013 |
| Hypotensive effect of Oxacom® containing a dinitrosyl iron complex with glutathione: animal studies and clinical trials on healthy volunteers.Nitric Oxide | No random groups | 2012 |
| Vaccination of goats with a glutathione peroxidase DNA vaccine induced partial protection against Haemonchus contortus infection.Vet Parasitol | No random groups | 2011 |
| [The study of hypotensive action of dinitrosyl-iron complex with glutathione containing drug oxacom in healthy volunteers].Kardiologiia | No random groups | 2011 |
| Linearity and stability of intravenous busulfan pharmacokinetics and the role of glutathione in busulfan elimination.Biol Blood Marrow Transplant | No random groups | 2011 |
| The addition of cysteine to the total sulphur amino acid requirement as methionine does not increase erythrocytes glutathione synthesis in the parenterally fed human neonate.Pediatr Res | No random groups | 2010 |
| Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome.J Hematol Oncol | No random groups | 2009 |
| Methionine-adequate cysteine-free diet does not limit erythrocyte glutathione synthesis in young healthy adult men.J Nutr | No random groups | 2008 |
| Mercury elimination with oral DMPS, DMSA, vitamin C, and glutathione: an observational clinical review.Altern Ther Health Med | No random groups | 2006 |
| [Increased urinary excretion of the neurotoxic side-chain metabolites of ifosphamide in children with polymorphism of the glutathione S-transferases genes].Med Wieku Rozwoj | No random groups | 2005 |
| Phase I study of TLK286 (glutathione S-transferase P1-1 activated glutathione analogue) in advanced refractory solid malignancies.Clin Cancer Res | No random groups | 2003 |
| Glutathione attenuates coronary constriction to acetylcholine in patients with coronary spastic angina.Am J Physiol Heart Circ Physiol | No random groups | 2001 |
| Intravenous ifosfamide/mesna is associated with depletion of plasma thiols without depletion of leukocyte glutathione.Clin Cancer Res | No random groups | 2000 |
| Intensive weekly chemotherapy for locally advanced gastric cancer using 5-fluorouracil, cisplatin, epidoxorubicin, 6S-leucovorin, glutathione and filgrastim: a report from the Italian Group for the Study of Digestive Tract Cancer (GISCAD).Br J Cancer | No random groups | 1998 |
| Intracoronary infusion of reduced glutathione improves endothelial vasomotor response to acetylcholine in human coronary circulation.Circulation | No random groups | 1998 |
| A pilot clinical trial of postoperative intensive weekly chemotherapy using cisplatin, epi-doxorubicin, 5-fluorouracil, 6S-leucovorin, glutathione and filgrastim in patients with resected gastric cancer.Tumori | No random groups | 1998 |
| Intensive weekly chemotherapy for advanced gastric cancer using fluorouracil, cisplatin, epi-doxorubicin, 6S-leucovorin, glutathione, and filgrastim: a report from the Italian Group for the Study of Digestive Tract Cancer.J Clin Oncol | No random groups | 1997 |
| Lack of glutathione conjugation of melphalan in the isolated in situ liver perfusion in humans.Cancer Res | No random groups | 1996 |
| Reduced intravenous glutathione in the treatment of early Parkinson's disease.Prog Neuropsychopharmacol Biol Psychiatry | No random groups | 1996 |
| Time-dependent pharmacodynamic models in cancer chemotherapy: population pharmacodynamic model for glutathione depletion following modulation by buthionine sulfoximine (BSO) in a Phase I trial of melphalan and BSO.Cancer Res | No random groups | 1995 |
| Systemic effects of S-nitroso-glutathione in the human following intravenous infusion.Br J Clin Pharmacol | No random groups | 1995 |
| Phase I trial of cisplatin in combination with glutathione.Gynecol Oncol | No random groups | 1994 |
| Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: an attempt at modulation of glutathione.J Clin Oncol | No random groups | 1994 |
| High-dose cisplatin and cyclophosphamide with glutathione in the treatment of advanced ovarian cancer.Ann Oncol | No random groups | 1993 |
| Intravenous Glutathione and Vitamin Supplementation Causing Stevens-Johnson Syndrome: A Case Report.J Burn Care Res | Case reports | 2025 |
| Concurrent infusion of glutathione, tranexamic acid, and Vitamin C as oral mesotherapeutic agents for management of gingival hyperpigmentation: A case series.J Conserv Dent Endod | Case reports | 2025 |
| Systemic Inflammatory Response Syndrome Following High-Dose Intravenous Glutathione-Containing Revitalising Solution in a Patient on Tirzepatide: A Case Report.Cureus | Case reports | 2025 |
| Glutathione Whitening Pills Induced Toxic Epidermal Necrolysis: An Unusual Case Confirmed by Enzyme-Linked Immunospot Assay and Liquid Chromatography-Mass Spectrometry.Dermatitis | Case reports | 2021 |
| The Use of Intravenous Glutathione for Symptom Management of Parkinson's Disease: A Case Report.Altern Ther Health Med | Case reports | 2018 |
| Effect of glutathione on the cadmium chelation of EDTA in a patient with cadmium intoxication.Hum Exp Toxicol | Case reports | 2011 |
| Complete regression of recurrent esophageal carcinoma with reduced expression of glutathione S-transferase-pi by treatment with continuous infusion of 5-fluorouracil and low-dose cisplatin infusion.Am J Gastroenterol | Case reports | 1999 |
| [Effect of AO-90, methionine-free amino acid injection, on the glutathione concentration in blood and tumor in patients with advanced gastric cancer].Gan To Kagaku Ryoho | Case reports | 1994 |
| Severe hepatic failure occurring with T61 ingestion in an attempted suicide. Early recovery with the use of intravenous infusion of reduced glutathione.Dig Dis Sci | Case reports | 1993 |
| Isolation and characterization of the glutathione-elliptinium conjugate in human urine.Anticancer Res | Case reports | 1987 |
| Selenium repletion and glutathione peroxidase--differential effects on plasma and red blood cell enzyme activity.Am J Clin Nutr | Case reports | 1985 |
| A review of the potential benefits and limitations of oral glutathione supplementation.Inflammopharmacology | Review of studies | 2026 |
| Glutathione for skin lightening via intravenous, oral, and topical routes: a critical narrative review of current evidence, safety, and the evidence-practice gap.J Med Life | Review of studies | 2026 |
| Glutathione Supplementation in Parenteral Nutrition to Prevent Oxidative Stress Related Complications in Preterm Infants: A Narrative Review of Preclinical Efficacy and Safety Profile.Nutrients | Review of studies | 2026 |
| Systematic Review of the Efficacy and Safety of Topical Glutathione in Dermatology.J Clin Aesthet Dermatol | Review of studies | 2025 |
| Intravenous glutathione should not be mismatched with ozone as an antioxidant therapy.Biomed Pharmacother | Review of studies | 2025 |
| Glutathione as a skin-lightening agent and in melasma: a systematic review.Int J Dermatol | Review of studies | 2025 |
| Exploring the Safety and Efficacy of Glutathione Supplementation for Skin Lightening: A Narrative Review.Cureus | Review of studies | 2025 |
| Which has a more protective effect against neuronal changes in the cingulate cortex of newborn rats of diabetic mothers: omega 3 or glutathione?Ultrastruct Pathol | Review of studies | 2025 |
| Systemic Glutathione as a Skin-Whitening Agent in Adult.Dermatol Res Pract | Review of studies | 2020 |
| The clinical effect of glutathione on skin color and other related skin conditions: A systematic review.J Cosmet Dermatol | Review of studies | 2019 |
| Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits.Pharmacol Ther | Review of studies | 2014 |
| Mitochondrial glutathione: a modulator of brain cell death.J Bioenerg Biomembr | Review of studies | 2004 |
| New insights into the pathogenesis of cystic fibrosis: pivotal role of glutathione system dysfunction and implications for therapy.Treat Respir Med | Review of studies | 2004 |
| Interaction between glutamine availability and metabolism of glycogen, tricarboxylic acid cycle intermediates and glutathione.J Nutr | Review of studies | 2001 |
| Therapeutic potential of glutathione.Wien Klin Wochenschr | Review of studies | 2000 |
| (-)Deprenyl increases the life span as well as activities of superoxide dismutase and catalase but not of glutathione peroxidase in selective brain regions in Fischer rats.Ann N Y Acad Sci | Review of studies | 1994 |
| Mitochondrial glutathione depletion in alcoholic liver disease.Alcohol | Review of studies | 1993 |
| New aspects of glutathione metabolism and translocation in mammals.Ciba Found Symp | Review of studies | 1979 |
| Glutathione/Selenite Interaction Products as Potent Vascular Smooth Muscle Tone Modulators with Antihypertensive Effects in Spontaneously Hypertensive Rats.Biol Trace Elem Res | In animals | 2026 |
| GLYAT deficiency protects against acetaminophen-induced liver injury by increasing glycine availability for glutathione synthesis.Biochem Pharmacol | In animals | 2026 |
| Effect of intravenous lipid and glutathione infusions on metabolism, inflammation, and immune functions of dairy cows.J Dairy Sci | In animals | 2026 |
| [Effects of glutathione on acute cutaneous photodamage in mice and its mechanism].Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi | In animals | 2026 |
| Targeted Disruption of Selenocysteine Lyase in Brown Adipocytes Controls Glutathione Peroxidase 1 and 4 Expression in Males.Biol Trace Elem Res | In animals | 2026 |
| Synergistic effect of glutathione and metformin mitigates testicular apoptosis by ameliorating gonadotropin hormones and gene expression in streptozotocin-induced diabetic male mice.Reprod Fertil Dev | In animals | 2026 |
| Niacin improves developmental ability by increasing glutathione levels and promoting male pronuclear formation in porcine oocytes grown in vitro.J Reprod Dev | In animals | 2026 |
| Duhuo jisheng decoction alleviates osteoarthritis progression by mitigating ferroptosis in chondrocytes via the nuclear factor erythroid 2-related factor 2/glutathione peroxidase 4 axis.J Ethnopharmacol | In animals | 2025 |
| Polystyrene nanoplastics exposure trigger cognitive impairment mitigated by luteolin modulated glucose-6-phosphate dehydrogenase/glutathione-dependent pathway.J Hazard Mater | In animals | 2025 |
| A novel pharmacological strategy using nanoparticles with glutathione and virgin coconut oil to treat gentamicin-induced acute renal failure in rats.Naunyn Schmiedebergs Arch Pharmacol | In animals | 2025 |
| Improved therapeutic index of the liposomal docetaxel-glutathione prepared by active click loading.Eur J Pharm Biopharm | In animals | 2024 |
| In vivo upstream factors of mouse hepatotoxic mechanism with sustained hepatic glutathione depletion: Acetaminophen metabolite-erythrocyte adducts and splenic macrophage-generated reactive oxygen species.Chem Biol Interact | In animals | 2024 |
| Fasting potentiates diclofenac-induced liver injury via inductions of oxidative/endoplasmic reticulum stresses and apoptosis, and inhibition of autophagy by depleting hepatic glutathione in mice.Food Chem Toxicol | In animals | 2024 |
| Glutathione Supplementation Prevents Neonatal Parenteral Nutrition-Induced Short- and Long-Term Epigenetic and Transcriptional Disruptions of Hepatic H2O2 Metabolism in Guinea Pigs.Nutrients | In animals | 2024 |
| Inhibition of glutathione generation in hepatic steatotic rats augments oxidative stress.Toxicol Mech Methods | In animals | 2023 |
| The Role of Reduced Glutathione on the Activity of Adenosine Deaminase, Antioxidative System, and Aluminum and Zinc Levels in Experimental Aluminum Toxicity.Biol Trace Elem Res | In animals | 2023 |
| Functional analysis of an overexpressed glutathione S-transferase BdGSTd5 involved in malathion and malaoxon detoxification in Bactrocera dorsalis.Pestic Biochem Physiol | In animals | 2023 |
| Elemene induces cell apoptosis via inhibiting glutathione synthesis in lung adenocarcinoma.J Ethnopharmacol | In animals | 2023 |
| Spinosad-associated modulation of select cytochrome P450s and glutathione S-transferases in the Colorado potato beetle, Leptinotarsa decemlineata.Arch Insect Biochem Physiol | In animals | 2023 |
| Mapping glycine uptake and its metabolic conversion to glutathione in mouse mammary tumors using functional mass spectrometry imaging.Free Radic Biol Med | In animals | 2022 |
| Temperature modulating the peroxidase-mimic activity of poly(N-isopropyl acrylamide) protected gold nanoparticles for colorimetric detection of glutathione.Spectrochim Acta A Mol Biomol Spectrosc | In animals | 2022 |
| Role and mechanism of REG2 depletion in insulin secretion augmented by glutathione peroxidase-1 overproduction.Redox Biol | In animals | 2022 |
| Targeted Delivery of Chemo-Sonodynamic Therapy via Brain Targeting, Glutathione-Consumable Polymeric Nanoparticles for Effective Brain Cancer Treatment.Adv Sci (Weinh) | In animals | 2022 |
| Multiple Infusion Start Time Mass Spectrometry Imaging of Dynamic SIL-Glutathione Biosynthesis Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization.J Proteome Res | In animals | 2022 |
| N-acetylcysteine facilitates extinction of cued fear memory in rats via reestablishing basolateral amygdala glutathione homeostasis.Acta Pharmacol Sin | In animals | 2022 |
| Comparison of three methods for in vivo quantification of glutathione in tissues of hypertensive rats.Free Radic Res | In animals | 2021 |
| Sirt1 deficiency upregulates glutathione metabolism to prevent hepatocellular carcinoma initiation in mice.Oncogene | In animals | 2021 |
| Effects of acute iron overload on Nrf2-related glutathione metabolism in rat brain.Biometals | In animals | 2021 |
| Glutathione-Responsive Gold Nanoparticles as Computed Tomography Contrast Agents for Hepatic Diseases.ACS Appl Bio Mater | In animals | 2021 |
| Glutathione ethyl ester reverses the deleterious effects of fentanyl on ventilation and arterial blood-gas chemistry while prolonging fentanyl-induced analgesia.Sci Rep | In animals | 2021 |
| Melanin-Decolorizing Activity of Antioxidant Enzymes, Glutathione Peroxidase, Thiol Peroxidase, and Catalase.Mol Biotechnol | In animals | 2021 |
| Recombinant glutathione-S-transferase A3 protein regulates the angiogenesis-related genes of erythrocytes in thiram induced tibial lesions.Res Vet Sci | In animals | 2020 |
| Extremely Small Iron Oxide Nanoparticle-Encapsulated Nanogels as a Glutathione-Responsive T1 Contrast Agent for Tumor-Targeted Magnetic Resonance Imaging.ACS Appl Mater Interfaces | In animals | 2020 |
| EFFECT OF MELATONIN INJECTIONS ON THE GLUTATHIONE SYSTEM IN HEART TISSUE OF RATS UNDER EXPERIMENTAL DIABETES.Georgian Med News | In animals | 2020 |
| Substitution of Dietary Sulfur Amino Acids by dl-2-Hydroxy-4-Methylthiobutyric Acid Reduces Fractional Glutathione Synthesis in Weaned Piglets.J Nutr | In animals | 2020 |
| Safety and efficacy of parenteral glutathione as a promising skin lightening agent: A controlled assessor blinded pharmacohistologic and ultrastructural study in an animal model.Dermatol Ther | In animals | 2020 |
| Dietary glutathione supplementation enhances antioxidant activity and protects against lipopolysaccharide-induced acute hepatopancreatic injury and cell apoptosis in Chinese mitten crab, Eriocheir sinensis.Fish Shellfish Immunol | In animals | 2020 |
| Extraction and Identification of Two Flavonoids in Phlomoides hyoscyamoides as an Endemic Plant of Iran: The Role of Quercetin in the Activation of the Glutathione Peroxidase, the Improvement of the Hydroxyproline and Protein Oxidation in Bile Duct-Ligated Rats.Curr Comput Aided Drug Des | In animals | 2020 |
| Glutathione Supplementation of Parenteral Nutrition Prevents Oxidative Stress and Sustains Protein Synthesis in Guinea Pig Model.Nutrients | In animals | 2019 |
| Immune system stimulation increases the plasma cysteine flux and whole-body glutathione synthesis rate in starter pigs1.J Anim Sci | In animals | 2019 |
| [Study of compound glutathione inosine injection effect on expression of regucalcin in liver tissue of rats with immune hepatic fibrosis].Zhonghua Gan Zang Bing Za Zhi | In animals | 2019 |
| Sperm-borne glutathione-S-transferase omega 2 accelerates the nuclear decondensation of spermatozoa during fertilization in mice†.Biol Reprod | In animals | 2019 |
| Two delta class glutathione S-transferases involved in the detoxification of malathion in Bactrocera dorsalis (Hendel).Pest Manag Sci | In animals | 2019 |
| EFFECTS OF 7-DAY MELATONIN INTRODUCTION ON THE HYDROGEN SULFIDE PRODUCTION AND GLUTATHIONE SYSTEM IN THE LIVER OF ALLOXAN INDUCED DIABETIC RATS.Georgian Med News | In animals | 2019 |
| Amplification of Tumor Oxidative Stresses with Liposomal Fenton Catalyst and Glutathione Inhibitor for Enhanced Cancer Chemotherapy and Radiotherapy.Nano Lett | In animals | 2019 |
| The synthesis and characterization of glutathione-modified superparamagnetic iron oxide nanoparticles and their distribution in rat brains after injection in substantia nigra.J Mater Sci Mater Med | In animals | 2018 |
| Glutathione peroxidase 4 participates in secondary brain injury through mediating ferroptosis in a rat model of intracerebral hemorrhage.Brain Res | In animals | 2018 |
| Glutathione peroxidase-1 overexpressing transgenic mice are protected from neurotoxicity induced by microcystin-leucine-arginine.Environ Toxicol | In animals | 2018 |
| Genetic overexpression of glutathione peroxidase-1 attenuates microcystin-leucine-arginine-induced memory impairment in mice.Neurochem Int | In animals | 2018 |
| Glutathione treatment of Japanese Black bull sperm prior to intracytoplasmic sperm injection promotes embryo development.J Reprod Dev | In animals | 2018 |
| Survival of rats bearing advanced intracerebral F 98 tumors after glutathione depletion and microbeam radiation therapy: conclusions from a pilot project.Radiat Oncol | In animals | 2018 |
| Distribution of Glutathione-Stabilized Gold Nanoparticles in Feline Fibrosarcomas and Their Role as a Drug Delivery System for Doxorubicin-Preclinical Studies in a Murine Model.Int J Mol Sci | In animals | 2018 |
| Quantification of glutathione in single cells from rat liver by microchip electrophoresis with chemiluminescence detection.Talanta | In animals | 2018 |
| S-allyl-glutathione improves experimental liver fibrosis by regulating Kupffer cell activation in rats.Am J Physiol Gastrointest Liver Physiol | In animals | 2018 |
| Glutathione has a more important role than metallothionein-I/II against inorganic mercury-induced acute renal toxicity.J Toxicol Sci | In animals | 2018 |
| Isochlorogenic acid C prevents enterovirus 71 infection via modulating redox homeostasis of glutathione.Sci Rep | In animals | 2017 |
| Apocynin protects against neurological damage induced by quinolinic acid by an increase in glutathione synthesis and Nrf2 levels.Neuroscience | In animals | 2017 |
| Motor dysfunction and alterations in glutathione concentration, cholinesterase activity, and BDNF expression in substantia nigra pars compacta in rats with pedunculopontine lesion.Neuroscience | In animals | 2017 |
| Sperm pretreatment with heparin and l-glutathione, sex-sorting, and double cryopreservation to improve intracytoplasmic sperm injection in bovine.Theriogenology | In animals | 2017 |
| Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation.Sci Signal | In a lab dish | 2019 |
| Glutathione and cysteine enhance porcine preimplantation embryo development in vitro after intracytoplasmic sperm injection.Theriogenology | In a lab dish | 2014 |
| Development and characterization of glutathione-conjugated albumin nanoparticles for improved brain delivery of hydrophilic fluorescent marker.Drug Deliv | In a lab dish | 2013 |
| Effects of glycyrrhizin on biliary transport and hepatic levels of glutathione in rats.Biopharm Drug Dispos | In a lab dish | 2012 |
| Caffeine and uric acid mediate glutathione synthesis for neuroprotection.Neuroscience | In a lab dish | 2011 |
| Identification of a thioselenurane intermediate in the reaction between phenylaminoalkyl selenoxides and glutathione.Arch Biochem Biophys | In a lab dish | 2011 |
| Estrogen selectively up-regulates the phospholipid hydroperoxide glutathione peroxidase in the oviducts.Endocrinology | In a lab dish | 2005 |
| Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid.Proc Natl Acad Sci U S A | In a lab dish | 2004 |
| Redox pacing of proteome turnover: influences of glutathione and ketonemia.Arch Biochem Biophys | In a lab dish | 2003 |
| Superoxide dismutase, catalase, glutathione peroxidase and NADPH oxidase in lead-induced hypertension.Kidney Int | In a lab dish | 2003 |
| Glutathione depletion with L-buthionine-(S,R)-sulfoximine demonstrates deleterious effects in acute pancreatitis of the rat.Dig Dis Sci | In a lab dish | 2002 |
| Multidrug resistance-associated protein2 (MRP2) plays an important role in the biliary excretion of glutathione conjugates of 4-hydroxynonenal.Free Radic Biol Med | In a lab dish | 2002 |
| Tissue lipid peroxidation and reduced glutathione depletion in hypochlorite-induced lung injury.Chest | In a lab dish | 2002 |
| Effect of buthionine sulphoximine, glutathione and methimazole on the renal disposition of cisplatin and on cisplatin-induced nephrotoxicity in rats: pharmacokinetic-toxicodynamic analysis.J Pharm Pharmacol | In a lab dish | 2000 |
| Developmental patterns of zygotes from transgenic female mice with elevated tissue glutathione.J Exp Zool | In a lab dish | 2000 |
| Melatonin maintains glutathione homeostasis in kainic acid-exposed rat brain tissues.FASEB J | In a lab dish | 1997 |
| Effect of acute Trypanosoma vivax infection on cattle erythrocyte glutathione and susceptibility to in vitro peroxidation.Vet Parasitol | In a lab dish | 1996 |
| Coenzyme A glutathione disulfide. A potent vasoconstrictor derived from the adrenal gland.Circ Res | In a lab dish | 1995 |
| Acute regulation of hepatic glutathione S-transferase by insulin and glucagon.Toxicol Lett | In a lab dish | 1995 |
| A protective effect of glutathione-dextran macromolecular conjugates on acetaminophen-induced hepatotoxicity dependent on molecular size.Biol Pharm Bull | In a lab dish | 1994 |
| K(+)-linked release of oxidized glutathione induced by tert-butyl hydroperoxide in perfused rat liver is independent of lipid peroxidation and cell death.Jpn J Pharmacol | In a lab dish | 1994 |
| Biphasic modifying effect of indole-3-carbinol on diethylnitrosamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley rats.Jpn J Cancer Res | In a lab dish | 1994 |
| K(+)-driven sinusoidal efflux of glutathione disulfide under oxidative stress in the perfused rat liver.FEBS Lett | In a lab dish | 1993 |
| Renal transport of glycine during glutathione replenishment in rats.Biochem Med Metab Biol | In a lab dish | 1993 |
| Antioxidative effect of protoporphyrin and increase of glutathione in protoporphyrin-administered rat liver.Biol Pharm Bull | In a lab dish | 1993 |
| Effects of in vitro ethanol and fetal ethanol exposure on glutathione stimulation of N-methyl-D-aspartate receptor function.Alcohol Clin Exp Res | In a lab dish | 1993 |
| Expression of rat liver reduced glutathione transport in Xenopus laevis oocytes.J Biol Chem | In a lab dish | 1993 |
| Physiological activities of S-(1,2-dicarboxyethyl)glutathione as an intrinsic tripeptide present in liver, heart and lens.Arzneimittelforschung | In a lab dish | 1992 |
| Glutathione as a primary osmotic driving force in hepatic bile formation.Am J Physiol | In a lab dish | 1992 |
| The relative importance of glutathione and metallothionein on protection of hepatotoxicity of menadione in rats.Chem Biol Interact | In a lab dish | 1992 |
| Thonningianin a mitigates intervertebral disc degeneration by inhibiting ferroptosis via chelating Fe2+ and regulating the adenosine monophosphate-activated protein kinase (AMPK)/ nuclear factor erythroid 2-related factor 2 (Nrf2)/ glutathione peroxidase 4 (GPX4) pathway.Phytomedicine | Other paper | 2026 |
| Preparation of an aptamer-based photoelectrochemical sensor for sequential detection of both mercury and glutathione in commercial skin lightening cosmetics.Analyst | Other paper | 2026 |
| Enzymatic/Mitochondrial Import Bottleneck in Sepsis with Possible Extensions to DIC: IV Glutathione and Hinokitiol as Potential Therapeutic Candidates.Int J Mol Sci | Other paper | 2026 |
| Improved Physicochemical Stability and Retinoblastoma Anticancer Activity of Salt-Caged Acid-Base Neutralized Melphalan Loaded in L-Glutathione and pH Responsive Fattigated Nanoparticles.Int J Nanomedicine | Other paper | 2026 |
| Quercetin attenuates peritoneal fibrosis by upregulating ferroptosis-related glutathione peroxidase 4 (GPX4) and solute carrier family 7 member 11 (SLC7A11) in MeT-5A and rat models: Supported by clinical mRNA expression data.Perit Dial Int | Other paper | 2026 |
| Glutathione-Triggered Nanodrug Disassembly for Enhanced Combined Ferroptosis and Photodynamic-Chemotherapy of Tumors.Adv Healthc Mater | Other paper | 2026 |
| Comparative efficacy of melatonin and glutathione in mitigating carboplatin-induced ovarian toxicity in rats.Clinics (Sao Paulo) | Other paper | 2026 |
| Glutathione-activatable bola dendrimers mediate tumor-specific cytosolic siRNA delivery via dynamic thiol-disulfide exchange.Biomater Sci | Other paper | 2026 |
| Engineering Biocompatible Glutathione-Capped Cu2ZnSnS4 Quantum Dots Toward Integrated Photothermal and Photodynamic Effects.Materials (Basel) | Other paper | 2026 |
| Glutathione-responsive deformable manganese-based nanomedicines for enhanced tumor-specific chemotherapy.RSC Adv | Other paper | 2026 |
| Chondrocyte-Targeted Nanoparticles Loaded with N-Acetylcysteine Protect Articular Cartilage and Attenuate Osteoarthritis by Inhibiting Ferroptosis via Glutathione Maintenance.Small Sci | Other paper | 2026 |
| The Complex Formation Between Ginsenosides and Glutathione Utilized in Cosmetics to Promote Transdermal Absorption and Mask the Bad Odor of Glutathione.Biomed Chromatogr | Other paper | 2026 |
| Kanglexin, a new anthraquinone compound, attenuates hepatic fibrosis by regulating the TGF-β/SMADS signaling pathway and glutathione metabolism.Int Immunopharmacol | Other paper | 2025 |
| Nerve Block-Assisted Intradermal Injection of Tranexamic Acid, Vitamin C, and Glutathione for Melasma: A Split-Face Comparative Study.Aesthetic Plast Surg | Other paper | 2025 |
| Ozone therapy and the role of the glutathione pathway.Inflammopharmacology | Other paper | 2025 |
| Theoretical studies of arbutin, glutathione, and sea cucumber extracts as inhibitors of tyrosinase.Sci Rep | Other paper | 2025 |
| Therapeutic effect of reduced glutathione combined with compound glycyrrhizin on acute liver injury in children and its effect on inflammatory cytokines: A retrospective study.Medicine (Baltimore) | Other paper | 2025 |
| Intranasal Delivery of Metabolically Resilient Glutathione: In Vivo Pharmacokinetic, Permeation, and Efficacy Studies.Mol Pharm | Other paper | 2025 |
| Manganese Phthalocyanine-Based Magnetic Core-Shell Composites with Peroxidase Mimetic Activity for Colorimetric Detection of Ascorbic Acid and Glutathione.Molecules | Other paper | 2025 |
| Assessment of the Therapeutic Effectiveness of Glutathione-Enhanced Mesenchymal Stem Cells in Rat Models of Chronic Bladder Ischemia-Induced Overactive Bladder and Detrusor Underactivity.Int J Stem Cells | Other paper | 2025 |
| Glutathione peroxidase 4 (GPX4) and obesity interact to impact tumor progression and treatment response in triple negative breast cancer.Cancer Metab | Other paper | 2025 |
| Insulin-Like Growth Factor 2 Secreted from Mesenchymal Stem Cells with High Glutathione Levels Alleviates Osteoarthritis via Paracrine Rejuvenation of Senescent Chondrocytes.Biomater Res | Other paper | 2025 |
| Tumor-targeted glutathione oxidation catalysis with ruthenium nanoreactors against hypoxic osteosarcoma.Nat Commun | Other paper | 2024 |
| Physical Compatibility of Reduced Glutathione for Injection With 44 Intravenous Drugs During Simulated Y-site Administration.Clin Ther | Other paper | 2024 |
| Optimizing Desolvation Conditions for Glutathione-Cross-Linked Bovine Serum Albumin Nanoparticles: Implication for Intravenous Drug Delivery.Cureus | Other paper | 2024 |
| Sequential Injection Analysis Method for the Determination of Glutathione in Pharmaceuticals.Sensors (Basel) | Other paper | 2024 |
| Dose-Dependent Prophylactic Efficacy of Filarial Antigens Glutathione-S-Transferase and Abundant Larval Transcript-2 against Brugia malayi Challenge in Mastomys.Can J Infect Dis Med Microbiol | Other paper | 2024 |
| Glutathione-responsive CD-MOFs co-loading honokiol and indocyanine green biomimetic active targeting to enhance photochemotherapy for breast cancer.Int J Pharm | Other paper | 2024 |
| Cannula Implantation Reduces the Severity of the Beta Amyloid Effect on Peroxidized Lipids and Glutathione Levels in the Brain of BALB/c Mice.Acta Naturae | Other paper | 2024 |
| Glutathione Induced In situ Synthesis of Cu Single-Atom Nanozymes with Anaerobic Glycolysis Metabolism Interference for Boosting Cuproptosis.Angew Chem Int Ed Engl | Other paper | 2024 |
| Protein intake affects erythrocyte glutathione synthesis in healthy adults aged ≥60 years in a repeated-measures trial.Am J Clin Nutr | Other paper | 2024 |
| The role of glutathione in stabilizing aromatic volatile organic compounds in Rougui Oolong tea: A comprehensive study from content to mechanisms.Food Chem | Other paper | 2024 |
| Microneedling with glutathione versus microneedling alone in treatment of facial melasma: Split-face comparative study.J Cosmet Dermatol | Other paper | 2023 |
| H2O2-responsive polymer prodrug nanoparticles with glutathione scavenger for enhanced chemo-photodynamic synergistic cancer therapy.Bioact Mater | Other paper | 2023 |
| Repeated Glutathione Sodium Salt Infusion May Counteract Contrast-Associated Acute Kidney Injury Occurrence in ST-Elevation Myocardial Infarction Patients Undergoing Primary PCI: A Randomized Subgroup Analysis of the GSH 2014 Trial.Life (Basel) | Other paper | 2023 |
| High-glutathione mesenchymal stem cells isolated using the FreSHtracer probe enhance cartilage regeneration in a rabbit chondral defect model.Biomater Res | Other paper | 2023 |
| Antioxidant, antihyperglycemic, and antihyperlipidemic properties of Chimonanthus salicifolius S. Y. Hu leaves in experimental animals: modulation of thioredoxin and glutathione systems, renal water reabsorption, and gut microbiota.Front Nutr | Other paper | 2023 |
| The Combined Treatment of Glutathione Sodium Salt and Ascorbic Acid for Preventing Contrast-Associated Acute Kidney Injury in ST-Elevation Myocardial Infarction Patients Undergoing Primary PCI: A Hypothesis to Be Validated.Antioxidants (Basel) | Other paper | 2023 |
| Holographically Activatable Nanoprobe via Glutathione/Albumin-Mediated Exponential Signal Amplification for High-Contrast Tumor Imaging.Adv Mater | Other paper | 2023 |
| A visual ratiometric fluorescence sensor for glutathione response based on MnO2 nanowires as an oxidant, quencher and recognition unit.Anal Methods | Other paper | 2023 |
| Automated approach for the evaluation of glutathione-S-transferase P1-1 inhibition by organometallic anticancer compounds.J Enzyme Inhib Med Chem | Other paper | 2022 |
| Exogenous L-Glutathione Improves Vitrification Outcomes in Murine Preimplantation Embryos.Antioxidants (Basel) | Other paper | 2022 |
| The role of glutathione conjugation on the transcellular transport process of PEGylated liposomes across the blood brain barrier.Int J Pharm | Other paper | 2022 |
| Efficacy and Safety of Carboxytherapy versus Combined Microneedling with Topical Glutathione in the Treatment of Patients with Periorbital Hyperpigmentation: An Evaluator-Blind, Split-Face, Controlled Pilot Clinical Trial.Indian J Dermatol | Other paper | 2022 |
| Xingnao Kaiqiao Acupuncture Combined with Butylphthalide Sodium Chloride Injection in the Treatment of Acute Cerebral Infarction and Its Effect on the Levels of Serum Malondialdehyde, Superoxide Dismutase, and Glutathione Peroxidase.Evid Based Complement Alternat Med | Other paper | 2022 |
| Novel Glutathione Activated Smart Probe for Photoacoustic Imaging, Photothermal Therapy, and Safe Postsurgery Treatment.ACS Appl Mater Interfaces | Other paper | 2022 |
| Bone Marrow Mesenchymal Stem Cells Exert Protective Effects After Ischemic Stroke Through Upregulation of Glutathione.Stem Cell Rev Rep | Other paper | 2022 |
| Turn-on signal fluorescence sensor based on DNA derived bio-dots/polydopamine nanoparticles for the detection of glutathione.RSC Adv | Other paper | 2022 |
| Pulmonary Delivery of Reactive Oxygen Species/Glutathione-Responsive Paclitaxel Dimeric Nanoparticles Improved Therapeutic Indices against Metastatic Lung Cancer.ACS Appl Mater Interfaces | Other paper | 2021 |
| Glutathione combined with mecobalamin in the treatment of chemotherapy-induced peripheral neuropathy in multiple myeloma: a retrospective clinical study.Ann Palliat Med | Other paper | 2021 |
| Melanin decolorization by lysosome-related extract in Saccharomyces cerevisiae modified to overproduce glutathione peroxidase.Appl Microbiol Biotechnol | Other paper | 2021 |
| Treating Acute Decompensated Heart Failure in Patients with COVID-19 Using Intravenous Nitroglycerin in 5% Glutathione.Am J Cardiovasc Drugs | Other paper | 2021 |
| Improved developmental potential of mouse vitrified-warmed oocytes achieved by culturing in recovery medium with glutathione ethyl ester (GSH-OEt).Reprod Med Biol | Other paper | 2021 |
| A glutathione-responsive polyphenol - Constructed nanodevice for double roles in apoptosis and ferroptosis.Colloids Surf B Biointerfaces | Other paper | 2021 |
| Evaluating Oral Glutathione Plus Ascorbic Acid, Alpha-lipoic Acid, and Zinc Aspartate as a Skin-lightening Agent: An Indonesian Multicenter, Randomized, Controlled Trial.J Clin Aesthet Dermatol | Other paper | 2021 |
| The effect of glutathione as adjuvant therapy on levels of TNF-α and IL-10 in wistar rat peritonitis model.Ann Med Surg (Lond) | Other paper | 2021 |
| Inhibition of miR-96-5p in the mouse brain increases glutathione levels by altering NOVA1 expression.Commun Biol | Other paper | 2021 |