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The US health department published a draft policy under which it would not act against pharmacies that make BPC-157 on a prescription for a named patient, until the FDA decides by rule. It is still not an approved medicine.
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GHRP-2

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Scientific papers

StudiesKind of studyYear
Effects of GHRP-2 and Cysteamine Administration on Growth Performance, Somatotropic Axis Hormone and Muscle Protein Deposition in Yaks (Bos grunniens) with Growth Retardation.PLoS OneRandom groups2016
Differential pulsatile secretagogue control of GH secretion in healthy men.Am J Physiol Regul Integr Comp PhysiolRandom groups2013
Regulated recovery of pulsatile growth hormone secretion from negative feedback: a preclinical investigation.Am J Physiol Regul Integr Comp PhysiolRandom groups2011
Gender, sex-steroid, and secretagogue-selective recovery from growth hormone-induced feedback in older women and men.J Clin Endocrinol MetabRandom groups2011
Complex regulation of GH autofeedback under dual-peptide drive: studies under a pharmacological GH and sex steroid clamp.Am J Physiol Endocrinol MetabRandom groups2011
Secretagogue type, sex-steroid milieu, and abdominal visceral adiposity individually determine secretagogue-stimulated cortisol secretion.Eur J EndocrinolRandom groups2010
Pre- versus postmenopausal age, estradiol, and peptide-secretagogue type determine pulsatile growth hormone secretion in healthy women: studies using submaximal agonist drive and an estrogen clamp.J Clin Endocrinol MetabRandom groups2010
Relative effects of estrogen, age, and visceral fat on pulsatile growth hormone secretion in healthy women.Am J Physiol Endocrinol MetabRandom groups2009
Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism.Eur J EndocrinolRandom groups2009
Factors other than sex steroids modulate GHRH and GHRP-2 efficacies in men: evaluation using a GnRH agonist/testosterone clamp.J Clin Endocrinol MetabRandom groups2009
Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp.J Clin Endocrinol MetabRandom groups2009
Determinants of GH-releasing hormone and GH-releasing peptide synergy in men.Am J Physiol Endocrinol MetabRandom groups2009
Aromatase and 5alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex steroid modulation of somatostatin and growth hormone secretagogue actions in healthy older men.J Clin Endocrinol MetabRandom groups2009
Gonadal status and body mass index jointly determine growth hormone (GH)-releasing hormone/GH-releasing peptide synergy in healthy men.J Clin Endocrinol MetabRandom groups2008
Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women.Am J Physiol Regul Integr Comp PhysiolRandom groups2007
Estimation of the size and shape of GH secretory bursts in healthy women using a physiological estradiol clamp and variable-waveform deconvolution model.Am J Physiol Regul Integr Comp PhysiolRandom groups2007
Obese subjects respond to the stimulatory effect of the ghrelin agonist growth hormone-releasing peptide-2 on food intake.Obesity (Silver Spring)Random groups2006
Testosterone supplementation in healthy older men drives GH and IGF-I secretion without potentiating peptidyl secretagogue efficacy.Eur J EndocrinolRandom groups2005
Short-term testosterone supplementation does not activate GH and IGF-I production in postmenopausal women.Clin Endocrinol (Oxf)Random groups2005
Joint mechanisms of impaired growth-hormone pulse renewal in aging men.J Clin Endocrinol MetabRandom groups2005
Determinants of dual secretagogue drive of burst-like growth hormone secretion in premenopausal women studied under a selective estradiol clamp.J Clin Endocrinol MetabRandom groups2005
Contributions of gender and systemic estradiol and testosterone concentrations to maximal secretagogue drive of burst-like growth hormone secretion in healthy middle-aged and older adults.J Clin Endocrinol MetabRandom groups2004
Activation of somatostatin-receptor subtype-2/-5 suppresses the mass, frequency, and irregularity of growth hormone (GH)-releasing peptide-2-stimulated GH secretion in men.J Clin Endocrinol MetabRandom groups2004
Short-term testosterone supplementation relieves growth hormone autonegative feedback in men.J Clin Endocrinol MetabRandom groups2004
Impact of estradiol supplementation on dual peptidyl drive of GH secretion in postmenopausal women.J Clin Endocrinol MetabRandom groups2002
E2 supplementation selectively relieves GH's autonegative feedback on GH-releasing peptide-2-stimulated GH secretion.J Clin Endocrinol MetabRandom groups2001
Reduction of free fatty acids by acipimox enhances the growth hormone (GH) responses to GH-releasing peptide 2 in elderly men.J Clin Endocrinol MetabRandom groups2000
Oral estradiol administration modulates continuous intravenous growth hormone (GH)-releasing peptide-2-driven GH secretion in postmenopausal women.J Clin Endocrinol MetabRandom groups2000
Tripartite neuroendocrine activation of the human growth hormone (GH) axis in women by continuous 24-hour GH-releasing peptide infusion: pulsatile, entropic, and nyctohemeral mechanisms.J Clin Endocrinol MetabRandom groups1999
Preservation of growth hormone secretion in response to growth hormone-releasing peptide-2 during prednisone therapy.MetabolismRandom groups1999
Reactivation of pituitary hormone release and metabolic improvement by infusion of growth hormone-releasing peptide and thyrotropin-releasing hormone in patients with protracted critical illness.J Clin Endocrinol MetabRandom groups1999
Tyr-Ala-Hexarelin, a synthetic octapeptide, possesses the same endocrine activities of Hexarelin and GHRP-2 in humans.J Endocrinol InvestRandom groups1999
Growth hormone-releasing peptide-2 infusion synchronizes growth hormone, thyrotrophin and prolactin release in prolonged critical illness.Eur J EndocrinolRandom groups1999
Leptin levels in protracted critical illness: effects of growth hormone-secretagogues and thyrotropin-releasing hormone.J Clin Endocrinol MetabRandom groups1998
Evidence against a role for the growth hormone-releasing peptide axis in human slow-wave sleep regulation.Am J PhysiolRandom groups1998
Neuroendocrinology of prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone secretagogues.J Clin Endocrinol MetabRandom groups1998
Thyrotrophin and prolactin release in prolonged critical illness: dynamics of spontaneous secretion and effects of growth hormone-secretagogues.Clin Endocrinol (Oxf)Random groups1997
The somatotropic axis in critical illness: effect of continuous growth hormone (GH)-releasing hormone and GH-releasing peptide-2 infusion.J Clin Endocrinol MetabRandom groups1997
Pituitary responsiveness to GH-releasing hormone, GH-releasing peptide-2 and thyrotrophin-releasing hormone in critical illness.Clin Endocrinol (Oxf)Random groups1996
Growth hormone (GH)-releasing effects of synthetic peptide GH-releasing peptide-2 and GH-releasing hormone (1-29NH2) in children with GH insufficiency and idiopathic short stature.MetabolismRandom groups1995
GH responses to intravenous bolus infusions of GH releasing hormone and GH releasing peptide 2 separately and in combination in adult volunteers.Clin Endocrinol (Oxf)Random groups1995
Investigation of the clinical significance of the growth hormone-releasing peptide-2 test for the diagnosis of secondary adrenal failure.Endocr JNo random groups2016
Secretagogues govern GH secretory-burst waveform and mass in healthy eugonadal and short-term hypogonadal men.Eur J EndocrinolNo random groups2008
Tripartite control of growth hormone secretion in women during controlled estradiol repletion.J Clin Endocrinol MetabNo random groups2007
GH response to hypoglycemia and clonidine in the GH-releasing hormone resistance syndrome.J Endocrinol InvestNo random groups2006
Changes in appetite and body weight in response to long-term oral administration of the ghrelin agonist GHRP-2 in growth hormone deficient children.J Pediatr Endocrinol MetabNo random groups2003
Growth hormone/insulin-like growth factor-1 response to acute and chronic growth hormone-releasing peptide-2, growth hormone-releasing hormone 1-44NH2 and in combination in older men and women with decreased growth hormone secretion.EndocrineNo random groups2001
Synergy of L-arginine and GHRP-2 stimulation of growth hormone in men and women: modulation by exercise.Am J Physiol Regul Integr Comp PhysiolNo random groups2000
A paradoxical gender dissociation within the growth hormone/insulin-like growth factor I axis during protracted critical illness.J Clin Endocrinol MetabNo random groups2000
Effects of eight months treatment with graded doses of a growth hormone (GH)-releasing peptide in GH-deficient children.J Clin Endocrinol MetabNo random groups1998
Pharmacokinetics and pharmacodynamics of growth hormone-releasing peptide-2: a phase I study in children.J Clin Endocrinol MetabNo random groups1998
Treatment effects of intranasal growth hormone releasing peptide-2 in children with short stature.J EndocrinolNo random groups1997
GHRP-2, GHRH and SRIF interrelationships during chronic administration of GHRP-2 to humans.J Pediatr Endocrinol MetabNo random groups1996
Diagnostic studies with intravenous and intranasal growth hormone-releasing peptide-2 in children of short stature.J Clin Endocrinol MetabNo random groups1995
One Case of Sudden Isolated Adrenocorticotropic Hormone (ACTH) Deficiency Diagnosed Based on Repeated Hypoglycemic Attacks.CureusCase reports2025
Idiopathic combined adrenocorticotropin and growth hormone deficiency mimicking chronic fatigue syndrome.BMJ Case RepCase reports2021
ICAM1-Negative Intravascular Large B-Cell Lymphoma of the Pituitary Gland: A Case Report and Literature Review.AACE Clin Case RepCase reports2021
Idiopathic and isolated adrenocorticotropic hormone deficiency presenting as continuous epigastric discomfort without symptoms of hypoglycemia: a case report.J Med Case RepCase reports2019
Secondary Adrenal Insufficiency Following Nivolumab Therapy in a Patient with Metastatic Renal Cell Carcinoma.Tokai J Exp Clin MedCase reports2017
Is there an undiscovered neurocircuit for regulating GH secretion? -Pitfalls of GHRP-2 and ITT as GH provocative tests-.Endocr JCase reports2010
Concordant and discordant adrenocorticotropin (ACTH) responses induced by growth hormone-releasing peptide-2 (GHRP-2), corticotropin-releasing hormone (CRH) and insulin-induced hypoglycemia in patients with hypothalamopituitary disorders: evidence for direct ACTH releasing activity of GHRP-2.Endocr JCase reports2010
Exaggerated response of adrenocorticotropic hormone to growth hormone-releasing peptide-2 test in Cushing's disease. Case report.Neurol Med Chir (Tokyo)Case reports2009
Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review.Sex Med RevReview of studies2026
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.Front Endocrinol (Lausanne)Review of studies2026
Pharmacotherapy in Cachexia: A Review of Endocrine Abnormalities and Steroid Pharmacotherapy.J Pain Palliat Care PharmacotherReview of studies2022
Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males.Transl Androl UrolReview of studies2020
The Safety and Efficacy of Growth Hormone Secretagogues.Sex Med RevReview of studies2018
Ghrelin Receptor Ligands Reaching Clinical Trials: From Peptides to Peptidomimetics; from Agonists to Antagonists.Horm Metab ResReview of studies2016
Adult growth hormone deficiency: current concepts.Neurol Med Chir (Tokyo)Review of studies2014
[Diagnosis and treatment of adult growth hormone deficiency (aGHD) resulting from brain injury--role of aGHD].Brain NerveReview of studies2008
Pralmorelin: GHRP 2, GPA 748, growth hormone-releasing peptide 2, KP-102 D, KP-102 LN, KP-102D, KP-102LN.Drugs R DReview of studies2004
Sex-steroid modulation of growth hormone (GH) secretory control: three-peptide ensemble regulation under dual feedback restraint by GH and IGF-I.EndocrineReview of studies2003
Gateways to clinical trials.Methods Find Exp Clin PharmacolReview of studies2002
Body composition, physical exercise, growth hormone and obesity.Eat Weight DisordReview of studies2001
Interactive regulation of postmenopausal growth hormone insulin-like growth factor axis by estrogen and growth hormone-releasing peptide-2.EndocrineReview of studies2001
Growth hormone secretagogue actions on the pituitary gland: multiple receptors for multiple ligands?Clin Exp Pharmacol PhysiolReview of studies2000
Growth hormone-releasing peptides and the cardiovascular system.Ann Endocrinol (Paris)Review of studies2000
Orally active growth hormone secretagogues: state of the art and clinical perspectives.Ann MedReview of studies1998
New GH secretagogues and potential usefulness in thalassemia.J Pediatr Endocrinol MetabReview of studies1998
Growth hormone-releasing peptides and their analogs.Front NeuroendocrinolReview of studies1998
Growth hormone-releasing peptides.Eur J EndocrinolReview of studies1997
Growth hormone-releasing peptides: clinical and basic aspects.Horm ResReview of studies1996
Diurnal and Daily Variations in Growth Hormone and Growth Hormone Stimulation Test in Male Cynomolgus Monkeys.In VivoIn animals2026
Growth Hormone-Releasing Peptide 2 May Be Associated With Decreased M1 Macrophage Production and Increased Histologic and Biomechanical Tendon-Bone Healing Properties in a Rat Rotator Cuff Tear Model.ArthroscopyIn animals2025
β1-adrenergic receptors mediate plasma acyl-ghrelin elevation and depressive-like behavior induced by chronic psychosocial stress.NeuropsychopharmacologyIn animals2019
Synthesis of Mono-PEGylated Growth Hormone Releasing Peptide-2 and Investigation of its Biological Activity.AAPS PharmSciTechIn animals2015
Ghrelin receptor agonist, GHRP-2, produces antinociceptive effects at the supraspinal level via the opioid receptor in mice.PeptidesIn animals2014
Intraportal infusion of ghrelin could inhibit glucose-stimulated GLP-1 secretion by enteric neural net in Wistar rat.Biomed Res IntIn animals2014
Attenuation of systemic morphine-induced analgesia by central administration of ghrelin and related peptides in mice.PeptidesIn animals2013
Doping control analysis of seven bioactive peptides in horse plasma by liquid chromatography-mass spectrometry.Anal Bioanal ChemIn animals2013
Des-acyl ghrelin exhibits pro-anabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats.Mol Cell EndocrinolIn animals2012
Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient little mice.Clinics (Sao Paulo)In animals2012
Growth hormone releasing peptide-2, a ghrelin agonist, attenuates lipopolysaccharide-induced acute lung injury in rats.Tohoku J Exp MedIn animals2010
Beneficial effects of growth hormone-releasing peptide on myocardial oxidative stress and left ventricular dysfunction in dilated cardiomyopathic hamsters.Circ JIn animals2010
Growth hormone-releasing peptide-2 stimulates secretion and synthesis of adrenocorticotropic hormone in mouse pituitary.Regul PeptIn animals2009
Ghrelin receptor agonist, GHRP-2, attenuates burn injury-induced MuRF-1 and MAFbx expression and muscle proteolysis in rats.PeptidesIn animals2009
GHRP-2 attenuates burn-induced dysfunctions in rodents.Adv Exp Med BiolIn animals2009
The effect of growth hormone releasing peptide-2 on upper gastrointestinal contractile activity and food intake in conscious dogs.J GastroenterolIn animals2009
Growth hormone releasing peptide 2 reverses anorexia associated with chemotherapy with 5-fluoruracil in colon cancer cell-bearing mice.World J GastroenterolIn animals2008
GHRP-2, a GHS-R agonist, directly acts on myocytes to attenuate the dexamethasone-induced expressions of muscle-specific ubiquitin ligases, Atrogin-1 and MuRF1.Life SciIn animals2008
GH-releasing peptide-2 administration prevents liver inflammatory response in endotoxemia.Am J Physiol Endocrinol MetabIn animals2008
Neither intravenous nor intracerebroventricular administration of obestatin affects the secretion of GH, PRL, TSH and ACTH in rats.Regul PeptIn animals2007
Differential regulation of GHRH-receptor and GHS-receptor expression by long-term in vitro treatment of ovine pituitary cells with GHRP-2 and GHRH.EndocrineIn animals2006
KP-102 (growth hormone-releasing peptide-2) attenuates ischemia/reperfusion injury in isolated rat hearts.Naunyn Schmiedebergs Arch PharmacolIn animals2006
Tissue deiodinase activity during prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone-releasing peptide-2.EndocrinologyIn animals2005
Ghrelin receptor agonist GHRP-2 prevents arthritis-induced increase in E3 ubiquitin-ligating enzymes MuRF1 and MAFbx gene expression in skeletal muscle.Am J Physiol Endocrinol MetabIn animals2005
Effects of long-term treatment with growth hormone-releasing peptide-2 in the GHRH knockout mouse.Am J Physiol Endocrinol MetabIn animals2005
Physiologically based pharmacokinetic model for pralmorelin hydrochloride in rats.Drug Metab DisposIn animals2005
Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats.Am J Physiol Endocrinol MetabIn animals2005
Effects of dietary protein and growth hormone-releasing peptide (GHRP-2) on plasma IGF-1 and IGFBPs in Holstein steers.Domest Anim EndocrinolIn animals2005
Effects of combined long-term treatment with a growth hormone-releasing hormone analogue and a growth hormone secretagogue in the growth hormone-releasing hormone knock out mouse.NeuroendocrinologyIn animals2005
ACTH releasing activity of KP-102 (GHRP-2) in rats is mediated mainly by release of CRF.Naunyn Schmiedebergs Arch PharmacolIn animals2005
Regulation of ghrelin gene expression in stomach and feeding response to a ghrelin analogue in two strains of rats.PeptidesIn animals2004
Effect of GHRH and GHRP-2 treatment in vitro on GH secretion and levels of GH, pituitary transcription factor-1, GHRH-receptor, GH-secretagogue-receptor and somatostatin receptor mRNAs in ovine pituitary cells.Eur J EndocrinolIn animals2004
General pharmacology of KP-102 (GHRP-2), a potent growth hormone-releasing peptide.ArzneimittelforschungIn animals2004
Pharmacological characteristics of KP-102 (GHRP-2), a potent growth hormone-releasing peptide.ArzneimittelforschungIn animals2004
Endocrine and metabolic effects of growth hormone (GH) compared with GH-releasing peptide, thyrotropin-releasing hormone, and insulin infusion in a rabbit model of prolonged critical illness.EndocrinologyIn animals2004
Development of an enzyme-linked immunosorbent assay for the measurement of plasma growth hormone (GH) levels in channel catfish (Ictalurus punctatus): assessment of environmental salinity and GH secretogogues on plasma GH levels.Gen Comp EndocrinolIn animals2003
Growth hormone-releasing peptide-2 reduces inward rectifying K+ currents via a PKA-cAMP-mediated signalling pathway in ovine somatotropes.J PhysiolIn animals2002
Chicken ghrelin and growth hormone-releasing peptide-2 inhibit food intake of neonatal chicks.Eur J PharmacolIn animals2002
The effect of two-day treatment of primary cultured ovine somatotropes with GHRP-2 on membrane voltage-gated K+ currents.EndocrinologyIn animals2002
Is GHRH receptor essential to GHRP-2-induced GH secretion in primary cultured rat pituitary cells?EndocrinologyIn animals2002
A novel in vivo rabbit model of hypercatabolic critical illness reveals a biphasic neuroendocrine stress response.EndocrinologyIn animals2002
GH-releasing peptide-2 increases fat mass in mice lacking NPY: indication for a crucial mediating role of hypothalamic agouti-related protein.EndocrinologyIn animals2002
Direct modification of somatotrope function by long-term leptin treatment of primary cultured ovine pituitary cells.EndocrinologyIn animals2001
The in vitro effect of leptin on growth hormone secretion from primary cultured ovine somatotrophs.EndocrineIn animals2001
Plasma growth hormone (GH) responses after administration of the peptidergic GH secretagogue KP102 into the oral cavity, rumen, abomasum and duodenum in adult goats.Domest Anim EndocrinolIn animals2001
Effects of the administration of growth hormone-releasing peptide-2 (GHRP-2) orally by gavage and in feed on growth hormone release in swine.Domest Anim EndocrinolIn animals2001
The effect of growth hormone-releasing peptide-2 (KP102) administration on plasma insulin-like growth factor (IGF)-1 and IGF-binding proteins in Holstein steers on different planes of nutrition.Domest Anim EndocrinolIn animals2000
The effects of growth hormone-releasing peptide-2 (GHRP-2) on the release of growth hormone and growth performance in swine.Domest Anim EndocrinolIn animals2000
Oral administration of peptidergic growth hormone (GH) secretagogue KP102 stimulates GH release in goats.Domest Anim EndocrinolIn animals1999
Pharmacokinetic evaluation of ipamorelin and other peptidyl growth hormone secretagogues with emphasis on nasal absorption.XenobioticaIn animals1998
Ipamorelin, the first selective growth hormone secretagogue.Eur J EndocrinolIn animals1998
A new series of highly potent growth hormone-releasing peptides derived from ipamorelin.J Med ChemIn animals1998
Intrahypothalamic perfusion of KP102 stimulates growth hormone release in goats.Endocr JIn animals1998
Effects of muscarinic and adrenergic blockade on growth hormone secretion induced by growth hormone-releasing peptide-2 (GHRP-2) in ovariectomized ewes.Endocr JIn animals1997
No desensitization of the growth hormone (GH) response between GH-releasing peptide-2 and GH-releasing factor in calves.J Anim SciIn animals1997
Mechanisms of action of growth hormone-releasing peptide-2 in bovine pituitary cells.J Anim SciIn animals1997
The role of protein kinase C in GH secretion induced by GH-releasing factor and GH-releasing peptides in cultured ovine somatotrophs.J EndocrinolIn animals1997
Growth hormone releasing peptides: a comparison of the growth hormone releasing activities of GHRP-2 and GHRP-6 in rat primary pituitary cells.Life SciIn animals1997
Characteristics of growth hormone secretion responsiveness to growth hormone-releasing peptide-2 (GHRP-2 or KP102) in calves.Endocr JIn animals1996
Differentiating hypothalamic from pituitary adrenal insufficiency: underlying causes and diagnostic utility of the corticotropin-releasing hormone and growth hormone-releasing peptide-2 stimulation tests.Endocr JOther paper2026
Possible Involvement of Hypothalamic Dysfunction in Long COVID Patients Characterized by Delayed Response to Gonadotropin-Releasing Hormone.Int J Mol SciOther paper2026
Benchmark for Setting ACTH Cell Dosage in Clinical Regenerative Medicine for Post-Operative Hypopituitarism.DiseasesOther paper2025
Literature-Based Discovery to Elucidate the Biological Links between Resistant Hypertension and COVID-19.Biology (Basel)Other paper2023
Assessment of anterior pituitary reserve capacity based on growth hormone response to growth hormone-releasing peptide-2 test in the elderly.Growth Horm IGF ResOther paper2023
Clinical Usefulness of the Growth Hormone-Releasing Peptide-2 Test for Hypothalamic-Pituitary Disorder.J Endocr SocOther paper2022
Association between overweight and growth hormone secretion in patients with non-functioning pituitary tumors.PLoS OneOther paper2022
Refractory hypoglycaemia in a localised gastrointestinal stromal tumour: Case report.Int J Surg Case RepOther paper2021
On the road of dried blood spot sampling for antidoping tests: Detection of GHRP-2 abuse.Drug Test AnalOther paper2021
Identification of potential Mpro inhibitors for the treatment of COVID-19 by using systematic virtual screening approach.Mol DiversOther paper2021
Determination of the immunostimulatory drug-glucosoaminyl-muramyl-dipeptide-in human plasma using HPLC-MS/MS and its application to a pharmacokinetic study.Biomed ChromatogrOther paper2020
Fully automated dried blood spot sample preparation enables the detection of lower molecular mass peptide and non-peptide doping agents by means of LC-HRMS.Anal Bioanal ChemOther paper2020
Preoperative growth hormone (GH) peak values during a GH releasing peptide-2 test reflect the severity of hypopituitarism and the postoperative recovery of GH secretion in patients with non-functioning pituitary adenomas.Endocr JOther paper2020
Detection of black market follistatin 344.Drug Test AnalOther paper2019
Glycine-modified growth hormone secretagogues identified in seized doping material.Drug Test AnalOther paper2019
Identification of a novel growth hormone releasing peptide (a glycine analogue of GHRP-2) in a seized injection vial.Drug Test AnalOther paper2019
Evaluation of growth hormone-releasing peptide-2 for diagnosis of thyrotropin-producing pituitary adenomas.Endocr JOther paper2018
Evaluation of Hypothalamic-Pituitary-Adrenal Axis by the GHRP2 Test: Comparison With the Insulin Tolerance Test.J Endocr SocOther paper2018
Growth Hormone Secretagogue Treatment in Hypogonadal Men Raises Serum Insulin-Like Growth Factor-1 Levels.Am J Mens HealthOther paper2017
Laparoscopic Sleeve Gastrectomy Resolves Low GHRP-2-Stimulated Growth Hormone Levels in Obese Patients.Obes SurgOther paper2017
Structure-activity relationship for peptídic growth hormone secretagogues.Drug Test AnalOther paper2017
Genetic and protein biomarkers in blood for the improved detection of GH abuse.J Pharm Biomed AnalOther paper2016
Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells.Int J Mol SciOther paper2016
Simplifying and expanding the screening for peptides <2 kDa by direct urine injection, liquid chromatography, and ion mobility mass spectrometry.J Sep SciOther paper2016
Determination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP-1, GHRP-2, GHRP-6, Hexarelin, and Ipamorelin.Drug Test AnalOther paper2015
One-year intranasal application of growth hormone releasing peptide-2 improves body weight and hypoglycemia in a severely emaciated anorexia nervosa patient.J Cachexia Sarcopenia MuscleOther paper2015
Detection of GHRP-2 and GHRP-6 in urine samples from athletes.Drug Test AnalOther paper2015
In vitro models for metabolic studies of small peptide hormones in sport drug testing.J Pept SciOther paper2015
Increased Secretion of Endogenous GH after Treatment with an Intranasal GH-releasing Peptide-2 Spray Does Not Promote Growth in Short Children with GH Deficiency.Clin Pediatr EndocrinolOther paper2014
A high-throughput LC-MS/MS screen for GHRP in equine and human urine, featuring peptide derivatization for improved chromatography.Drug Test AnalOther paper2014
Adult growth hormone deficiency: current concepts.Neurol Med Chir (Tokyo)Other paper2014
Urinary growth hormone level and insulin-like growth factor-1 standard deviation score (IGF-SDS) can discriminate adult patients with severe growth hormone deficiency.Endocr JOther paper2013
The arginine and GHRP-2 tests as alternatives to the insulin tolerance test for the diagnosis of adult GH deficiency in Japanese patients: a comparison.Endocr JOther paper2013
Metabolism of growth hormone releasing peptides.Anal ChemOther paper2012
Determination of prohibited, small peptides in urine for sports drug testing by means of nano-liquid chromatography/benchtop quadrupole orbitrap tandem-mass spectrometry.J Chromatogr AOther paper2012
Growth hormone secretagogues: out of competition.Anal Bioanal ChemOther paper2012
Doping control analysis of selected peptide hormones using LC-MS(/MS).Forensic Sci IntOther paper2011
High-throughput screening for various classes of doping agents using a new 'dilute-and-shoot' liquid chromatography-tandem mass spectrometry multi-target approach.Drug Test AnalOther paper2011
Functional interaction of bone morphogenetic protein and growth hormone releasing peptide in adrenocorticotropin regulation by corticotrope cells.Mol Cell EndocrinolOther paper2011
Determination of growth hormone releasing peptides (GHRP) and their major metabolites in human urine for doping controls by means of liquid chromatography mass spectrometry.Anal Bioanal ChemOther paper2011
Influence of intravenous administration of growth hormone releasing peptide-2 (GHRP-2) on detection of growth hormone doping: growth hormone isoform profiles in Japanese male subjects.Drug Test AnalOther paper2010
Determination of growth hormone secretagogue pralmorelin (GHRP-2) and its metabolite in human urine by liquid chromatography/electrospray ionization tandem mass spectrometry.Rapid Commun Mass SpectromOther paper2010
Growth hormone response to GH-releasing peptide-2 in children.J Pediatr Endocrinol MetabOther paper2010
Comparison of pituitary-adrenal responsiveness between insulin tolerance test and growth hormone-releasing peptide-2 test: a pilot study.PeptidesOther paper2010
Identification of the growth-hormone-releasing peptide-2 (GHRP-2) in a nutritional supplement.Drug Test AnalOther paper2010
GH-releasing peptide-2 does not stimulate arginine vasopressin secretion in healthy men.Endocr JOther paper2010
Growth hormone-releasing peptide-2 suppresses vascular oxidative stress in ApoE-/- mice but does not reduce atherosclerosis.EndocrinologyOther paper2009
Diagnostic usefulness of the growth hormone-releasing peptide-2 test as a substitute for the insulin tolerance test in hypopituitarism.Endocr JOther paper2008
Validation of growth-hormone-releasing peptide 2 for the diagnosis of adult growth hormone deficiency.Nat Clin Pract Endocrinol MetabOther paper2008
Complementary secretagogue pairs unmask prominent gender-related contrasts in mechanisms of growth hormone pulse renewal in young adults.J Clin Endocrinol MetabOther paper2005
Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men.J Clin Endocrinol MetabOther paper2005
Stimulation of growth hormone secretion from seabream pituitary cells in primary culture by growth hormone secretagogues is independent of growth hormone transcription.Comp Biochem Physiol C Toxicol PharmacolOther paper2004
Dual secretagogue drive of burst-like growth hormone secretion in postmenopausal compared with premenopausal women studied under an experimental estradiol clamp.J Clin Endocrinol MetabOther paper2004
Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women.J Clin Endocrinol MetabOther paper2004
Gateways to clinical trials.Methods Find Exp Clin PharmacolOther paper2003
Growth hormone-releasing peptide-2 stimulates GH secretion in GH-deficient patients with mutated GH-releasing hormone receptor.J Clin Endocrinol MetabOther paper2001
Somatostatin octapeptides (lanreotide, octreotide, vapreotide, and their analogs) share the growth hormone-releasing peptide receptor in the human pituitary gland.EndocrineOther paper2001
Short-term estradiol supplementation augments growth hormone (GH) secretory responsiveness to dose-varying GH-releasing peptide infusions in healthy postmenopausal women.J Clin Endocrinol MetabOther paper2001

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