# GHRP-2

pralmorelin

https://graded.pl/en/substances/ghrp-2 · Checked: Not yet

Preliminary version. The editors have not finished checking this card, and grades may change.

A peptide that raises growth hormone. Japan uses it to test for a shortage of that hormone. Not approved in the EU or US.

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## Short answers

### Does GHRP-2 work?

A peptide that raises growth hormone. Japan uses it to test for a shortage of that hormone. Not approved in the EU or US. Muscle mass: grade D, not clear. One study with random groups in 33 critically ill men over 5 days: it restored growth hormone release and IGF-1. Muscle was not measured, and the men were not healthy.

### Is GHRP-2 legal?

PL: No approval. The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. EU: No approval. The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). US: No approval. The FDA drug register has no such medicine.

### Is GHRP-2 banned in sport?

Banned in sport, WADA 2026.

### Is GHRP-2 safe?

Little data. In people it was given mainly once, as a test for a shortage of growth hormone. We found no data on longer use.

## What studies show

| | | | |
|---|---|---|---|
| Muscle mass | D | Not clear | One study with random groups in 33 critically ill men over 5 days: it restored growth hormone release and IGF-1. Muscle was not measured, and the men were not healthy. |

## Studies we have read

- The combined administration of GH-releasing peptide-2 (GHRP-2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP-2 alone. (Clin Endocrinol (Oxf) 2002; Random groups, n=33) https://pubmed.ncbi.nlm.nih.gov/12030918/

## Is it legal

- PL: No approval. The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. https://www.ema.europa.eu/en/documents/other/article-57-product-data_en.xlsx (Checked: Not yet)
- EU: No approval. The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). https://www.ema.europa.eu/en/documents/other/article-57-product-data_en.xlsx (Checked: Not yet)
- US: No approval. The FDA drug register has no such medicine. https://www.accessdata.fda.gov/scripts/cder/daf/ (Checked: Not yet)

## Doping

Banned in sport, WADA 2026. https://zoek.officielebekendmakingen.nl/trb-2026-25.html

## How much research exists

- Scientific papers: 223
- Studies with random groups: 42
- Registered studies in people: 0
- These are search results. A count shows how much exists, not how good the studies are. 1 Nov 2026.

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Open data: CC BY 4.0, https://creativecommons.org/licenses/by/4.0/