A peptide described in the 1970s and named for its effect on sleep in animals. No such medicine exists. We have not graded the studies yet. The number of papers in the databases is shown on the page.

PL: No approval. The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. EU: No approval. The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). US: No approval. No approved medicine. FDA advisers discussed on 23–24 July 2026 whether pharmacies could make it to order.

Not known. We found no safety study that would allow an assessment.

Short entry. It holds facts from official registers, with no study grade. We are still writing the full description.

DSIP

delta sleep-inducing peptide · emideltide

A peptide described in the 1970s and named for its effect on sleep in animals. No such medicine exists.

This site is for information and education only. It does not promote or encourage the use or purchase of the substances described and is not medical advice. Many are not authorised as medicines and their safety has not been established. We sell nothing and have no ties to sellers. For health decisions, consult a doctor.

Type: Peptide
Stage: Work stopped
Safety: Not known
Doping: May be banned, WADA 2026
Risk of fakes: Not known
Checked: Not yet

Doping. It is not on the WADA list, but WADA also bans substances that no health authority has approved, so it may be banned.

Safety. We found no safety study that would allow an assessment.

Risk of fakes. We found no tests of products sold outside pharmacies.

Is it legal

Where	Status		Checked
PL	No approval	The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. Source	Not yet
EU	No approval	The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). Source	Not yet
US	No approval	No approved medicine. FDA advisers discussed on 23–24 July 2026 whether pharmacies could make it to order. Source	Not yet

How much research exists

Scientific papers: 463
Studies with random groups: 6
Registered studies in people: 1

These are search results. A count shows how much exists, not how good the studies are. 1 Nov 2026.

Reported side effects

What doctors, patients and companies reported to the US medicines agency (FDA), and single cases described in medical journals. A report says what happened to someone after taking the substance. It does not prove the substance caused it, and it does not say how often it happens. Reports do not change any grade.

Reports to the FDA (USA)

Reports: 0
Of these, serious: 0

The FDA has no reports. That is not a sign of safety: almost nobody reports substances from outside pharmacies.

Cases described in medical journals

We found no published case of harm.

FDA reports come from openFDA, cases from a PubMed search. The editors have not read these cases yet. Titles stay in the original language. As of 3 Nov 2026.

More papers we found

Studies	Kind of study	Year
An RCT study on the feasibility of anterior transpedicular screw fixation in the cervicothoracic junction.Eur Spine J	Random groups	2016
Delta sleep-inducing peptide alters bispectral index, the electroencephalogram and heart rate variability when used as an adjunct to isoflurane anaesthesia.Eur J Anaesthesiol	Random groups	2009
Different effects of delta-sleep-inducing peptide on arginine-vasopressin and ACTH secretion in normal men.Horm Res	Random groups	1994
Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients. A double-blind study.Neuropsychobiology	Random groups	1992
Reduction of immunoreactive ACTH in plasma following intravenous injection of delta sleep-inducing peptide in man.Psychoneuroendocrinology	Random groups	1989
[Using deltalicin for the treatment of patients with diabetic retinopathy].Eksp Klin Farmakol	No random groups	2014
Delta-sleep-inducing peptide does not affect CRH and meal-induced ACTH and cortisol secretion.Psychoneuroendocrinology	No random groups	1995
Plasma concentration of nine hormones and neurotransmitters during usual activities or constant bed rest for 34 H.Chronobiol Int	No random groups	1994

We found these papers automatically in PubMed. The editors have not read them yet, and they do not affect any grade. Titles stay in the original language.

All papers and studies we found (183)

Short answers

Does DSIP work?: A peptide described in the 1970s and named for its effect on sleep in animals. No such medicine exists. We have not graded the studies yet. The number of papers in the databases is shown on the page.
Is DSIP legal?: PL: No approval. The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. EU: No approval. The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). US: No approval. No approved medicine. FDA advisers discussed on 23–24 July 2026 whether pharmacies could make it to order.
Is DSIP banned in sport?: May be banned, WADA 2026. It is not on the WADA list, but WADA also bans substances that no health authority has approved, so it may be banned.
Is DSIP safe?: Not known. We found no safety study that would allow an assessment.

Plain text for machines