Graded
The US health department published a draft policy under which it would not act against pharmacies that make BPC-157 on a prescription for a named patient, until the FDA decides by rule. It is still not an approved medicine.
PL

Strength

Strength depends on the nervous system and technique as well as muscle size, so more mass does not always mean more strength.

First, legal options with stronger studies

  • Planned heavy strength training with gradually heavier loads.
  • Learning technique and planning rest.
  • Creatine, which is allowed in sport.

What studies found for specific substances

Sorted alphabetically. Order does not imply a recommendation.

  • CMK-677

    More body mass without fat did not bring more strength or better function in older adults. A study after hip fracture was stopped early for safety reasons.

  • COstarine

    Physical function improved in an early study, while the two largest studies went in opposite directions. Top strength was not what they tested.

  • DRAD-140

    One study in female mice: after 10 weeks strength did not differ from the control group, and the mice were frailer and more likely to die.

  • BRapamycin

    Two small studies of older adults showed no gain in function, and one suggested a weaker response to training.

  • ASomatropin

    Strength did not improve in older men, and a review of healthy young adults says it may not improve. One study saw better sprinting, which faded 6 weeks after stopping.

  • CSS-31

    A large study in a rare muscle disease found no improvement, after small studies gave unclear results. The FDA approved it on a fast track to improve muscle strength in Barth syndrome, another rare disease. None of this concerns healthy people.